Flexible low-cost cardiovascular risk marker biosensor for point-of-care applications

Shilpa Sivashankar, Christos Sapsanis, Ulrich Buttner, Khaled N. Salama

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


The detection and quantification of protein on a laser written flexible substrate for point-of-care applications are described. A unique way of etching gold on polyethylene terephthalate (PET) substrate is demonstrated by reducing the damage that may be caused on PET sheets otherwise. On the basis of the quantity of the C-reactive protein (CRP) present in the sample, the risk of cardiac disease can be assessed. This hsCRP test is incorporated to detect the presence of CRP on a PET laser patterned biosensor. Concentrations of 1, 2, and 10 mg/l were chosen to assess the risk of cardiac diseases as per the limits set by the American Heart Association.
Original languageEnglish (US)
Pages (from-to)1746-1748
Number of pages3
JournalElectronics Letters
Issue number22
StatePublished - Oct 22 2015


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