TY - JOUR
T1 - Fluxomics - new metabolomics approaches to monitor metabolic pathways
AU - Emwas, Abdul-Hamid M.
AU - Szczepski, Kacper
AU - Al-Younis (Elyounis), Inas (Enas) M.
AU - Lachowicz, Joanna Izabela
AU - Jaremko, Mariusz
N1 - KAUST Repository Item: Exported on 2022-01-25
PY - 2022
Y1 - 2022
N2 - Fluxomics is a new omics research field that measures the rates of all intracellular fluxes in the central metabolism of biological systems. Fluxomics is one of the most relevant approaches to investigate metabolic phenotypes. Metabolic flux using 13C-labeled molecules is increasingly used to monitor metabolic pathways. By determining metabolic pathways, researchers can probe the corresponding gene-RNA and protein-metabolite interaction networks in actual time. Thus, fluxomics can be used to understand metabolic pathways and has many applications in biotechnology and pharmacology. Here, we briefly introduce fluxomics with a review of the most recent studies and common analytical tools.
AB - Fluxomics is a new omics research field that measures the rates of all intracellular fluxes in the central metabolism of biological systems. Fluxomics is one of the most relevant approaches to investigate metabolic phenotypes. Metabolic flux using 13C-labeled molecules is increasingly used to monitor metabolic pathways. By determining metabolic pathways, researchers can probe the corresponding gene-RNA and protein-metabolite interaction networks in actual time. Thus, fluxomics can be used to understand metabolic pathways and has many applications in biotechnology and pharmacology. Here, we briefly introduce fluxomics with a review of the most recent studies and common analytical tools.
UR - http://hdl.handle.net/10754/675112
UR - https://www.frontiersin.org/articles/10.3389/fphar.2022.805782/abstract
M3 - Article
SN - 1663-9812
JO - Frontiers in Pharmacology
JF - Frontiers in Pharmacology
ER -