Folding Up of Gold Nanoparticle Strings into Plasmonic Vesicles for Enhanced Photoacoustic Imaging

Yijing Liu; Jie He; Kuikun Yang; Chenglin Yi; Yi Liu; Liming Nie; Niveen M. Khashab; Xiaoyuan Chen; Zhihong Nie

doi:10.1002/anie.201508616

Folding Up of Gold Nanoparticle Strings into Plasmonic Vesicles for Enhanced Photoacoustic Imaging

Yijing Liu, Jie He, Kuikun Yang, Chenglin Yi, Yi Liu, Liming Nie, Niveen M. Khashab, Xiaoyuan Chen, Zhihong Nie

Research output: Contribution to journal › Article › peer-review

169 Scopus citations

Abstract

The stepwise self-assembly of hollow plasmonic vesicles with vesicular membranes containing strings of gold nanoparticles (NPs) is reported. The formation of chain vesicles can be controlled by tuning the density of the polymer ligands on the surface of the gold NPs. The strong absorption of the chain vesicles in the near-infrared (NIR) region leads to a much higher efficiency in photoacoustic (PA) imaging than for non-chain vesicles. The chain vesicles were further employed for the encapsulation of drugs and the NIR light triggered release of payloads. This work not only offers a new platform for controlling the hierarchical self-assembly of NPs, but also demonstrates that the physical properties of the materials can be tailored by controlling the spatial arrangement of NPs within assemblies to achieve a better performance in biomedical applications.

Original language	English (US)
Pages (from-to)	15809-15812
Number of pages	4
Journal	Angewandte Chemie International Edition
Volume	54
Issue number	52
DOIs	https://doi.org/10.1002/anie.201508616 https://doi.org/10.1002/ange.201508616
State	Published - Nov 11 2015

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@article{bee297f5ac7f48a494ad9d9b82acc5a5,

title = "Folding Up of Gold Nanoparticle Strings into Plasmonic Vesicles for Enhanced Photoacoustic Imaging",

abstract = "The stepwise self-assembly of hollow plasmonic vesicles with vesicular membranes containing strings of gold nanoparticles (NPs) is reported. The formation of chain vesicles can be controlled by tuning the density of the polymer ligands on the surface of the gold NPs. The strong absorption of the chain vesicles in the near-infrared (NIR) region leads to a much higher efficiency in photoacoustic (PA) imaging than for non-chain vesicles. The chain vesicles were further employed for the encapsulation of drugs and the NIR light triggered release of payloads. This work not only offers a new platform for controlling the hierarchical self-assembly of NPs, but also demonstrates that the physical properties of the materials can be tailored by controlling the spatial arrangement of NPs within assemblies to achieve a better performance in biomedical applications.",

author = "Yijing Liu and Jie He and Kuikun Yang and Chenglin Yi and Yi Liu and Liming Nie and Khashab, {Niveen M.} and Xiaoyuan Chen and Zhihong Nie",

note = "KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: This work was funded by a National Science Foundation (NSF) CAREER award (DMR-1255377), the ACS Petroleum Research Fund (PRF 53461-DNI7), a 3M non-tenured faculty award, and the Intramural Research Program of the National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health. We acknowledge support by the Maryland NanoCenter and its NispLab.",

year = "2015",

month = nov,

day = "11",

doi = "10.1002/anie.201508616",

language = "English (US)",

volume = "54",

pages = "15809--15812",

journal = "Angewandte Chemie International Edition",

issn = "1433-7851",

publisher = "John Wiley and Sons Ltd",

number = "52",

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T1 - Folding Up of Gold Nanoparticle Strings into Plasmonic Vesicles for Enhanced Photoacoustic Imaging

AU - Liu, Yijing

AU - He, Jie

AU - Yang, Kuikun

AU - Yi, Chenglin

AU - Liu, Yi

AU - Nie, Liming

AU - Khashab, Niveen M.

AU - Chen, Xiaoyuan

AU - Nie, Zhihong

N1 - KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: This work was funded by a National Science Foundation (NSF) CAREER award (DMR-1255377), the ACS Petroleum Research Fund (PRF 53461-DNI7), a 3M non-tenured faculty award, and the Intramural Research Program of the National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health. We acknowledge support by the Maryland NanoCenter and its NispLab.

PY - 2015/11/11

Y1 - 2015/11/11

N2 - The stepwise self-assembly of hollow plasmonic vesicles with vesicular membranes containing strings of gold nanoparticles (NPs) is reported. The formation of chain vesicles can be controlled by tuning the density of the polymer ligands on the surface of the gold NPs. The strong absorption of the chain vesicles in the near-infrared (NIR) region leads to a much higher efficiency in photoacoustic (PA) imaging than for non-chain vesicles. The chain vesicles were further employed for the encapsulation of drugs and the NIR light triggered release of payloads. This work not only offers a new platform for controlling the hierarchical self-assembly of NPs, but also demonstrates that the physical properties of the materials can be tailored by controlling the spatial arrangement of NPs within assemblies to achieve a better performance in biomedical applications.

AB - The stepwise self-assembly of hollow plasmonic vesicles with vesicular membranes containing strings of gold nanoparticles (NPs) is reported. The formation of chain vesicles can be controlled by tuning the density of the polymer ligands on the surface of the gold NPs. The strong absorption of the chain vesicles in the near-infrared (NIR) region leads to a much higher efficiency in photoacoustic (PA) imaging than for non-chain vesicles. The chain vesicles were further employed for the encapsulation of drugs and the NIR light triggered release of payloads. This work not only offers a new platform for controlling the hierarchical self-assembly of NPs, but also demonstrates that the physical properties of the materials can be tailored by controlling the spatial arrangement of NPs within assemblies to achieve a better performance in biomedical applications.

UR - http://hdl.handle.net/10754/623137

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DO - 10.1002/anie.201508616

M3 - Article

C2 - 26555318

SN - 1433-7851

VL - 54

SP - 15809

EP - 15812

JO - Angewandte Chemie International Edition

JF - Angewandte Chemie International Edition

IS - 52

ER -

Folding Up of Gold Nanoparticle Strings into Plasmonic Vesicles for Enhanced Photoacoustic Imaging

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