Gene expression data analysis in the membership embedding space: A constructive approach

M. Filippone, F. Masulli, S. Rovetta

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

Exploratory analysis of genomic data sets using unsupervised clustering techniques is often affected by problems due to the small cardinality and high dimensionality of the data set. A way to alleviate those problems lies in performing clustering in an embedding space where each data point is represented by a vector of its memberships to fuzzy sets characterized by a set of probes selected from the data set. This approach has been demonstrated to lead to significant improvements with respect the application of clustering algorithms in the original space and in the distance embedding space. In this paper we propose a constructive technique based on Simulated Annealing able to select sets of probes of small cardinality and supporting high quality clustering solutions.

Original languageEnglish (US)
Title of host publicationApplied Artificial Intelligence - Proceedings of the 7th International FLINS Conference, FLINS 2006
EditorsPierre D'Hondt, Etienne E. Kerre, Da Ruan, Martine De Cock, Mike Nachtegael, Paolo F. Fantoni
PublisherWorld Scientific Publishing Co. Pte Ltd
Pages617-624
Number of pages8
ISBN (Electronic)9812566902, 9789812566904
DOIs
StatePublished - 2006
EventApplied Artificial Intelligence - 7th International Fuzzy Logic and Intelligent Technologies in Nuclear Science Conference, FLINS 2006 - Genova, Italy
Duration: Aug 29 2006Aug 31 2006

Publication series

NameApplied Artificial Intelligence - Proceedings of the 7th International FLINS Conference, FLINS 2006

Conference

ConferenceApplied Artificial Intelligence - 7th International Fuzzy Logic and Intelligent Technologies in Nuclear Science Conference, FLINS 2006
Country/TerritoryItaly
CityGenova
Period08/29/0608/31/06

ASJC Scopus subject areas

  • Information Systems
  • Computational Theory and Mathematics
  • Nuclear and High Energy Physics

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