"Glass transition" in peptides: Temperature and pressure effects

P. Papadopoulos*, G. Floudas, I. Schnell, H. A. Klok, T. Aliferis, H. Iatrou, N. Hadjichristidis

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


We report on the origin of the liquid-to-glass transition in a series of oligopeptides of γ -benzyl- L -glutamate up to the polymer (PBLG), and in Poly- Z - L -lysine (PZLL) and Polyglycine (PGly) using dielectric spectroscopy as a function of temperature and pressure. We show that temperature is the dominant control variable of the dynamics associated with the peptidic "glass transition." This is an intrinsic feature of the peptide dynamics, irrespective of the type of amino acid and of the peptide secondary structure. The influence of the type of secondary structure (α helix vs Β sheet) on the liquid-to-glass dynamics is discussed.

Original languageEnglish (US)
Article number224906
Issue number22
StatePublished - Jun 8 2005
Externally publishedYes

ASJC Scopus subject areas

  • General Physics and Astronomy
  • Physical and Theoretical Chemistry


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