TY - JOUR
T1 - Green synthesized gold nanoparticles decorated graphene oxide for sensitive determination of chloramphenicol in milk, powdered milk, honey and eye drops
AU - Karthik, R.
AU - Govindasamy, Mani
AU - Chen, Shen Ming
AU - Mani, Veerappan
AU - Lou, Bih Show
AU - Devasenathipathy, Rajkumar
AU - Hou, Yu Shen
AU - Elangovan, A.
N1 - Generated from Scopus record by KAUST IRTS on 2023-09-21
PY - 2016/8/1
Y1 - 2016/8/1
N2 - A simple and rapid green synthesis using Bischofia javanica Blume leaves as reducing agent was developed for the preparation of gold nanoparticles (AuNPs). AuNPs decorated graphene oxide (AuNPs/GO) was prepared and employed for the sensitive amperometric determination of chloramphenicol. The green biosynthesis requires less than 40 s to reduce gold salts to AuNPs. The formations of AuNPs and AuNPs/GO were evaluated by scanning electron and atomic force microscopies, UV-Visible and energy dispersive X-ray spectroscopies, X-ray diffraction studies, and electrochemical methods. AuNPs/GO composite film modified electrode was fabricated and shown excellent electrocatalytic ability towards chloramphenicol. Under optimal conditions, the amperometric sensing platform has delivered wide linear range of 1.5-2.95 μM, low detection limit of 0.25 μM and high sensitivity of 3.81 μA μM-1 cm-2. The developed sensor exhibited good repeatability and reproducibility, anti-interference ability and long-term storage stability. Practical feasibility of the sensor has been demonstrated in food samples (milk, powdered milk and honey) and pharmaceutical sample (eye drops). The green synthesized AuNPs/GO composite has great potential for analysis of food samples in food safety measures.
AB - A simple and rapid green synthesis using Bischofia javanica Blume leaves as reducing agent was developed for the preparation of gold nanoparticles (AuNPs). AuNPs decorated graphene oxide (AuNPs/GO) was prepared and employed for the sensitive amperometric determination of chloramphenicol. The green biosynthesis requires less than 40 s to reduce gold salts to AuNPs. The formations of AuNPs and AuNPs/GO were evaluated by scanning electron and atomic force microscopies, UV-Visible and energy dispersive X-ray spectroscopies, X-ray diffraction studies, and electrochemical methods. AuNPs/GO composite film modified electrode was fabricated and shown excellent electrocatalytic ability towards chloramphenicol. Under optimal conditions, the amperometric sensing platform has delivered wide linear range of 1.5-2.95 μM, low detection limit of 0.25 μM and high sensitivity of 3.81 μA μM-1 cm-2. The developed sensor exhibited good repeatability and reproducibility, anti-interference ability and long-term storage stability. Practical feasibility of the sensor has been demonstrated in food samples (milk, powdered milk and honey) and pharmaceutical sample (eye drops). The green synthesized AuNPs/GO composite has great potential for analysis of food samples in food safety measures.
UR - https://linkinghub.elsevier.com/retrieve/pii/S0021979716302648
UR - http://www.scopus.com/inward/record.url?scp=84966708440&partnerID=8YFLogxK
U2 - 10.1016/j.jcis.2016.04.044
DO - 10.1016/j.jcis.2016.04.044
M3 - Article
SN - 1095-7103
VL - 475
SP - 46
EP - 56
JO - Journal of Colloid and Interface Science
JF - Journal of Colloid and Interface Science
ER -