TY - JOUR
T1 - Herpesvirus in the oral cavity of children with leukaemia and its impact on the oral bacterial community profile
AU - Bezerra, Tacíria M.
AU - Ferreira, Dennis C.
AU - Carmo, Flávia L.
AU - Pinheiro, Raquel
AU - Leite, Deborah C.A.
AU - Cavalcante, Fernanda S.
AU - Belinho, Raquel A.
AU - Peixoto, Raquel S.
AU - Rosado, Alexandre S.
AU - Dos Santos, Kátia R.N.
AU - Castro, Gloria F.B.A.
N1 - Generated from Scopus record by KAUST IRTS on 2021-02-16
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Aims This cross-sectional study investigated the association between eight herpesviruses and the bacterial community profiles from the oral cavity of children with and without leukaemia. Methods Sixty participants (aged 3-13), divided into the leukaemia group (LG) and healthy group (HG), were evaluated. Collection of medical data, intraoral examination and collection of clinical specimens were carried out. Single PCR and nested-PCR techniques were used to identify the viral types; denaturing gradient gel electrophoresis (DGGE) and real-time PCR techniques were used to evaluate the profile and abundance of bacterial communities. Results All the children with leukaemia were positive for at least one type of herpesvirus, compared with healthy participants (33.3%; p
AB - Aims This cross-sectional study investigated the association between eight herpesviruses and the bacterial community profiles from the oral cavity of children with and without leukaemia. Methods Sixty participants (aged 3-13), divided into the leukaemia group (LG) and healthy group (HG), were evaluated. Collection of medical data, intraoral examination and collection of clinical specimens were carried out. Single PCR and nested-PCR techniques were used to identify the viral types; denaturing gradient gel electrophoresis (DGGE) and real-time PCR techniques were used to evaluate the profile and abundance of bacterial communities. Results All the children with leukaemia were positive for at least one type of herpesvirus, compared with healthy participants (33.3%; p
UR - http://jcp.bmj.com/lookup/doi/10.1136/jclinpath-2014-202668
UR - http://www.scopus.com/inward/record.url?scp=84923321584&partnerID=8YFLogxK
U2 - 10.1136/jclinpath-2014-202668
DO - 10.1136/jclinpath-2014-202668
M3 - Article
SN - 1472-4146
VL - 68
SP - 222
EP - 228
JO - Journal of Clinical Pathology
JF - Journal of Clinical Pathology
IS - 3
ER -