Abstract
Successful derivation of pancreatic progenitors from human embryonic stem cells (hESCs) in vitro and further differentiation towards functional β cells in vivo may create the possibility of using hESC-derived pancreatic progenitors (PPs), instead of derived β cells, as an alternative transplantable source in β cell replacement therapy. Here we discuss present approaches, as well as future alternatives, in the fields of basic and clinic research on β cell differentiation, derivation and transplantation.
Original language | English (US) |
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Pages (from-to) | 592-594 |
Number of pages | 3 |
Journal | Cell research |
Volume | 23 |
Issue number | 5 |
DOIs | |
State | Published - May 2013 |
Externally published | Yes |
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology