Heterogeneous chemo-, regio- and diastereoselective hydrogenation of steroidic alpha-diketone

Valérie Gertosio; Catherine C. Santini; Jean Marie Basset; François Bayard; Jean Buendia; Michel Vivat

doi:10.1016/S1381-1169(98)00277-5

Heterogeneous chemo-, regio- and diastereoselective hydrogenation of steroidic alpha-diketone

Valérie Gertosio, Catherine C. Santini^*, Jean Marie Basset, François Bayard, Jean Buendia, Michel Vivat

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Supported catalysts, Rh/SiO₂, Ru/SiO₂, Pd/SiO₂, Pt/SiO₂ and Pd/C reduce methyloate of 3α-acetyl-11,12-dioxo-5β-cholan-24-oic acid 1 into the vicinal hydroxyketone 11-oxo,12β-OH 2 in 100% chemo-, regio- and diastereoselectivity at 100% of conversion.

Original language	English (US)
Pages (from-to)	141-145
Number of pages	5
Journal	Journal of Molecular Catalysis A: Chemical
Volume	142
Issue number	2
DOIs	https://doi.org/10.1016/S1381-1169(98)00277-5
State	Published - Jun 10 1999
Externally published	Yes

Keywords

Chemo-, regio-, diastereoselective hydrogenation
Heterogeneous catalysis
Steroid

ASJC Scopus subject areas

Catalysis
Process Chemistry and Technology
Physical and Theoretical Chemistry

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10.1016/S1381-1169(98)00277-5

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title = "Heterogeneous chemo-, regio- and diastereoselective hydrogenation of steroidic alpha-diketone",

abstract = "Supported catalysts, Rh/SiO2, Ru/SiO2, Pd/SiO2, Pt/SiO2 and Pd/C reduce methyloate of 3α-acetyl-11,12-dioxo-5β-cholan-24-oic acid 1 into the vicinal hydroxyketone 11-oxo,12β-OH 2 in 100% chemo-, regio- and diastereoselectivity at 100% of conversion.",

keywords = "Chemo-, regio-, diastereoselective hydrogenation, Heterogeneous catalysis, Steroid",

author = "Val{\'e}rie Gertosio and Santini, {Catherine C.} and Basset, {Jean Marie} and Fran{\c c}ois Bayard and Jean Buendia and Michel Vivat",

year = "1999",

month = jun,

day = "10",

doi = "10.1016/S1381-1169(98)00277-5",

language = "English (US)",

volume = "142",

pages = "141--145",

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TY - JOUR

T1 - Heterogeneous chemo-, regio- and diastereoselective hydrogenation of steroidic alpha-diketone

AU - Gertosio, Valérie

AU - Santini, Catherine C.

AU - Basset, Jean Marie

AU - Bayard, François

AU - Buendia, Jean

AU - Vivat, Michel

PY - 1999/6/10

Y1 - 1999/6/10

N2 - Supported catalysts, Rh/SiO2, Ru/SiO2, Pd/SiO2, Pt/SiO2 and Pd/C reduce methyloate of 3α-acetyl-11,12-dioxo-5β-cholan-24-oic acid 1 into the vicinal hydroxyketone 11-oxo,12β-OH 2 in 100% chemo-, regio- and diastereoselectivity at 100% of conversion.

AB - Supported catalysts, Rh/SiO2, Ru/SiO2, Pd/SiO2, Pt/SiO2 and Pd/C reduce methyloate of 3α-acetyl-11,12-dioxo-5β-cholan-24-oic acid 1 into the vicinal hydroxyketone 11-oxo,12β-OH 2 in 100% chemo-, regio- and diastereoselectivity at 100% of conversion.

KW - Chemo-, regio-, diastereoselective hydrogenation

KW - Heterogeneous catalysis

KW - Steroid

UR - http://www.scopus.com/inward/record.url?scp=0033542362&partnerID=8YFLogxK

U2 - 10.1016/S1381-1169(98)00277-5

DO - 10.1016/S1381-1169(98)00277-5

M3 - Article

AN - SCOPUS:0033542362

SN - 1381-1169

VL - 142

SP - 141

EP - 145

JO - Journal of Molecular Catalysis A: Chemical

JF - Journal of Molecular Catalysis A: Chemical

IS - 2

ER -

Heterogeneous chemo-, regio- and diastereoselective hydrogenation of steroidic alpha-diketone

Abstract

Keywords

ASJC Scopus subject areas

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