TY - JOUR
T1 - Highly antibacterial rGO/Cu2O nanocomposite from a biomass precursor: Synthesis, performance, and mechanism
AU - Chen, Mingguang
AU - Li, Zhi
AU - Chen, Long
N1 - KAUST Repository Item: Exported on 2021-02-24
Acknowledgements: This work was funded by the University of California, Riverside.
PY - 2019/9/11
Y1 - 2019/9/11
N2 - Reduced graphene oxide (rGO) has been widely used to fabricate electronics, sensors, photodetectors,and in other applications. However, the antibacterial performance of pristine rGO is relatively weak. The application of rGO in biomedical devices, smart food packaging, and water desalination membranes requires further improvement of rGO’s antibacterial abilities. Copper(I) oxide (Cu2O) is an effective antibacterial agent, which denatures protein and enhances the permeability of cell membranes. In this work, we report a simple method of synthesizing a highly antibacterial rGO/Cu2O nanocomposite from cellulose acetate, a derivative of abundant natural cellulose. The synthesized rGO/Cu2O nanocomposite was thoroughly characterized by Raman spectroscopy, X-ray powder diffraction (XRD), X-ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM), scanning electron microscopy (SEM), high-resolution transmission electron microscopy (HRTEM), and scanning transmission electron microscopy (STEM). Then, the antibacterial abilities of rGO/Cu2O nanocomposite were evaluated and a bactericidal mechanism was revealed from the molecular biology perspective. Results indicate that our synthesized rGO/Cu2O nanocomposite owns strong antibacterial activity, mainly stemming from the uniformly incorporated Cu2O nanocrystals with a lateral size of 5–40 nm.
AB - Reduced graphene oxide (rGO) has been widely used to fabricate electronics, sensors, photodetectors,and in other applications. However, the antibacterial performance of pristine rGO is relatively weak. The application of rGO in biomedical devices, smart food packaging, and water desalination membranes requires further improvement of rGO’s antibacterial abilities. Copper(I) oxide (Cu2O) is an effective antibacterial agent, which denatures protein and enhances the permeability of cell membranes. In this work, we report a simple method of synthesizing a highly antibacterial rGO/Cu2O nanocomposite from cellulose acetate, a derivative of abundant natural cellulose. The synthesized rGO/Cu2O nanocomposite was thoroughly characterized by Raman spectroscopy, X-ray powder diffraction (XRD), X-ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM), scanning electron microscopy (SEM), high-resolution transmission electron microscopy (HRTEM), and scanning transmission electron microscopy (STEM). Then, the antibacterial abilities of rGO/Cu2O nanocomposite were evaluated and a bactericidal mechanism was revealed from the molecular biology perspective. Results indicate that our synthesized rGO/Cu2O nanocomposite owns strong antibacterial activity, mainly stemming from the uniformly incorporated Cu2O nanocrystals with a lateral size of 5–40 nm.
UR - http://hdl.handle.net/10754/667604
UR - https://linkinghub.elsevier.com/retrieve/pii/S2589965119300595
U2 - 10.1016/j.nanoms.2019.09.005
DO - 10.1016/j.nanoms.2019.09.005
M3 - Article
SN - 2589-9651
VL - 2
SP - 172
EP - 179
JO - Nano Materials Science
JF - Nano Materials Science
IS - 2
ER -