Highly-Sensitive Magnetic Tunnel Junction Based Flow Cytometer

Selma Amara; Ride Bu; Meshal Alawein; Nouf Alsharif; Mohammed Asadullah Khan; Yan Wen; Xixiang Zhang; Jürgen Kosel; Hossein Fariborzi

doi:10.1109/memea.2018.8438652

Highly-Sensitive Magnetic Tunnel Junction Based Flow Cytometer

Selma Amara, Ride Bu, Meshal Alawein, Nouf Alsharif, Mohammed Asadullah Khan, Yan Wen, Xixiang Zhang, Jürgen Kosel, Hossein Fariborzi

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Scopus citations

Abstract

Flow cytometers are important instruments for biological and biomedical analyses. These instruments are large and expensive, and researchers are continuously striving to come up with smaller, cheaper, and more energy-efficient flow cytometers. In this work, we present a highly-sensitive magnetic tunnel junction (MTJ) based flow cytometer. An externally magnetized magnetic beads labeling cells were placed above an MTJ sensor that can measure the stray field surrounding the beads. It was found that each time labeled cells pass through the sensitive area of the sensor, a peak of signal was observed. The results demonstrate a novel MTJ based flow cytometer design approach for accurate detection of magnetically labeled cells.

Original language	English (US)
Title of host publication	2018 IEEE International Symposium on Medical Measurements and Applications (MeMeA)
Publisher	Institute of Electrical and Electronics Engineers (IEEE)
ISBN (Print)	9781538633922
DOIs	https://doi.org/10.1109/memea.2018.8438652
State	Published - Aug 20 2018

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10.1109/memea.2018.8438652

https://repository.kaust.edu.sa/bitstream/10754/628472/1/08438652.pdf

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@inproceedings{8990f526c91d415a98e2e5ef8819ea01,

title = "Highly-Sensitive Magnetic Tunnel Junction Based Flow Cytometer",

abstract = "Flow cytometers are important instruments for biological and biomedical analyses. These instruments are large and expensive, and researchers are continuously striving to come up with smaller, cheaper, and more energy-efficient flow cytometers. In this work, we present a highly-sensitive magnetic tunnel junction (MTJ) based flow cytometer. An externally magnetized magnetic beads labeling cells were placed above an MTJ sensor that can measure the stray field surrounding the beads. It was found that each time labeled cells pass through the sensitive area of the sensor, a peak of signal was observed. The results demonstrate a novel MTJ based flow cytometer design approach for accurate detection of magnetically labeled cells.",

author = "Selma Amara and Ride Bu and Meshal Alawein and Nouf Alsharif and Khan, {Mohammed Asadullah} and Yan Wen and Xixiang Zhang and J{\"u}rgen Kosel and Hossein Fariborzi",

note = "KAUST Repository Item: Exported on 2021-02-19 Acknowledgements: Research reported in this publication was supported by the King Abdullah University of Science and Technology (KAUST).",

year = "2018",

month = aug,

day = "20",

doi = "10.1109/memea.2018.8438652",

language = "English (US)",

isbn = "9781538633922",

booktitle = "2018 IEEE International Symposium on Medical Measurements and Applications (MeMeA)",

publisher = "Institute of Electrical and Electronics Engineers (IEEE)",

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TY - GEN

T1 - Highly-Sensitive Magnetic Tunnel Junction Based Flow Cytometer

AU - Amara, Selma

AU - Bu, Ride

AU - Alawein, Meshal

AU - Alsharif, Nouf

AU - Khan, Mohammed Asadullah

AU - Wen, Yan

AU - Zhang, Xixiang

AU - Kosel, Jürgen

AU - Fariborzi, Hossein

N1 - KAUST Repository Item: Exported on 2021-02-19 Acknowledgements: Research reported in this publication was supported by the King Abdullah University of Science and Technology (KAUST).

PY - 2018/8/20

Y1 - 2018/8/20

N2 - Flow cytometers are important instruments for biological and biomedical analyses. These instruments are large and expensive, and researchers are continuously striving to come up with smaller, cheaper, and more energy-efficient flow cytometers. In this work, we present a highly-sensitive magnetic tunnel junction (MTJ) based flow cytometer. An externally magnetized magnetic beads labeling cells were placed above an MTJ sensor that can measure the stray field surrounding the beads. It was found that each time labeled cells pass through the sensitive area of the sensor, a peak of signal was observed. The results demonstrate a novel MTJ based flow cytometer design approach for accurate detection of magnetically labeled cells.

AB - Flow cytometers are important instruments for biological and biomedical analyses. These instruments are large and expensive, and researchers are continuously striving to come up with smaller, cheaper, and more energy-efficient flow cytometers. In this work, we present a highly-sensitive magnetic tunnel junction (MTJ) based flow cytometer. An externally magnetized magnetic beads labeling cells were placed above an MTJ sensor that can measure the stray field surrounding the beads. It was found that each time labeled cells pass through the sensitive area of the sensor, a peak of signal was observed. The results demonstrate a novel MTJ based flow cytometer design approach for accurate detection of magnetically labeled cells.

UR - http://hdl.handle.net/10754/628472

UR - https://ieeexplore.ieee.org/document/8438652/

UR - http://www.scopus.com/inward/record.url?scp=85053153909&partnerID=8YFLogxK

U2 - 10.1109/memea.2018.8438652

DO - 10.1109/memea.2018.8438652

M3 - Conference contribution

AN - SCOPUS:85053153909

SN - 9781538633922

BT - 2018 IEEE International Symposium on Medical Measurements and Applications (MeMeA)

PB - Institute of Electrical and Electronics Engineers (IEEE)

ER -

Highly-Sensitive Magnetic Tunnel Junction Based Flow Cytometer

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