TY - JOUR
T1 - Hologenome analysis of two marine sponges with different microbiomes
AU - Ryu, Tae Woo
AU - Seridi, Loqmane
AU - Moitinho-Silva, Lucas
AU - Oates, Matthew
AU - Liew, Yi Jin
AU - Mavromatis, Charalampos Harris
AU - Wang, Xiaolei
AU - Haywood, Annika
AU - Lafi, Feras Fawzi
AU - Kupresanin, Marija
AU - Sougrat, Rachid
AU - Alzahrani, Majed A.
AU - Giles, Emily
AU - Ghosheh, Yanal
AU - Schunter, Celia Marei
AU - Baumgarten, Sebastian
AU - Berumen, Michael L.
AU - Gao, Xin
AU - Aranda, Manuel
AU - Foret, Sylvain
AU - Gough, Julian
AU - Voolstra, Christian R.
AU - Hentschel, Ute
AU - Ravasi, Timothy
N1 - KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: This work was supported by the King Abdullah University of Science and Technology. LMS was supported by a grant of the German Excellence Initiative to the Graduate School of Life Sciences, University of Wuerzburg. We thank the KAUST Core Lab for performing the sequencing and assisting with the genome-size analysis. We acknowledge Till Rothig (KAUST) for contributing to the sponge sample collection, Christine Gernert (University of Wurzburg) for assisting with the TEM analysis, and Sebastian Fraune (University of Kiel) for reading the manuscript critically. We also thank several anonymous reviewers for constructive comments.
PY - 2016/2/29
Y1 - 2016/2/29
N2 - Background
Sponges (Porifera) harbor distinct microbial consortia within their mesohyl interior. We herein analysed the hologenomes of Stylissa carteri and Xestospongia testudinaria, which notably differ in their microbiome content.
Results
Our analysis revealed that S. carteri has an expanded repertoire of immunological domains, specifically Scavenger Receptor Cysteine-Rich (SRCR)-like domains, compared to X. testudinaria. On the microbial side, metatranscriptome analyses revealed an overrepresentation of potential symbiosis-related domains in X. testudinaria.
Conclusions
Our findings provide genomic insights into the molecular mechanisms underlying host-symbiont coevolution and may serve as a roadmap for future hologenome analyses.
AB - Background
Sponges (Porifera) harbor distinct microbial consortia within their mesohyl interior. We herein analysed the hologenomes of Stylissa carteri and Xestospongia testudinaria, which notably differ in their microbiome content.
Results
Our analysis revealed that S. carteri has an expanded repertoire of immunological domains, specifically Scavenger Receptor Cysteine-Rich (SRCR)-like domains, compared to X. testudinaria. On the microbial side, metatranscriptome analyses revealed an overrepresentation of potential symbiosis-related domains in X. testudinaria.
Conclusions
Our findings provide genomic insights into the molecular mechanisms underlying host-symbiont coevolution and may serve as a roadmap for future hologenome analyses.
UR - http://hdl.handle.net/10754/600476
UR - http://www.biomedcentral.com/1471-2164/17/158
UR - http://www.scopus.com/inward/record.url?scp=84978763678&partnerID=8YFLogxK
U2 - 10.1186/s12864-016-2501-0
DO - 10.1186/s12864-016-2501-0
M3 - Article
C2 - 26926518
SN - 1471-2164
VL - 17
JO - BMC Genomics
JF - BMC Genomics
IS - 1
ER -
