Identification of promoter regions and regulatory sites.

Victor Soloviev*, Ilham A. Shahmuradov, Asaf A. Salamov

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

138 Scopus citations

Abstract

Promoter sequences are the main regulatory elements of gene expression. Their recognition by computer algorithms is fundamental for understanding gene expression patterns, cell specificity and development. This chapter describes the advanced approaches to identify promoters in animal, plant and bacterial sequences. Also, we discuss an approach to identify statistically significant regulatory motifs in genomic sequences.

Original languageEnglish (US)
Pages (from-to)57-83
Number of pages27
JournalMethods in molecular biology (Clifton, N.J.)
Volume674
DOIs
StatePublished - 2010
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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