TY - JOUR
T1 - Improving your target-template alignment with MODalign.
AU - Barbato, Alessandro
AU - Benkert, Pascal
AU - Schwede, Torsten
AU - Tramontano, Anna
AU - Kosinski, Jan
N1 - KAUST Repository Item: Exported on 2020-10-01
Acknowledged KAUST grant number(s): KUK-I1-012-43
Acknowledgements: KAUST Award No. KUK-I1-012-43 made by King Abdullah University of Science and Technology (KAUST), Fondazione Roma, the Italian Ministry of Health, Contract No. onc_ord 25/07, FIRB PROTEOMICA, and European Molecular Biology Organization (EMBO) long-term fellowship to J.K.
This publication acknowledges KAUST support, but has no KAUST affiliated authors.
PY - 2012/2/4
Y1 - 2012/2/4
N2 - SUMMARY: MODalign is an interactive web-based tool aimed at helping protein structure modelers to inspect and manually modify the alignment between the sequences of a target protein and of its template(s). It interactively computes, displays and, upon modification of the target-template alignment, updates the multiple sequence alignments of the two protein families, their conservation score, secondary structure and solvent accessibility values, and local quality scores of the implied three-dimensional model(s). Although it has been designed to simplify the target-template alignment step in modeling, it is suitable for all cases where a sequence alignment needs to be inspected in the context of other biological information. AVAILABILITY AND IMPLEMENTATION: Freely available on the web at http://modorama.biocomputing.it/modalign. Website implemented in HTML and JavaScript with all major browsers supported. CONTACT: [email protected].
AB - SUMMARY: MODalign is an interactive web-based tool aimed at helping protein structure modelers to inspect and manually modify the alignment between the sequences of a target protein and of its template(s). It interactively computes, displays and, upon modification of the target-template alignment, updates the multiple sequence alignments of the two protein families, their conservation score, secondary structure and solvent accessibility values, and local quality scores of the implied three-dimensional model(s). Although it has been designed to simplify the target-template alignment step in modeling, it is suitable for all cases where a sequence alignment needs to be inspected in the context of other biological information. AVAILABILITY AND IMPLEMENTATION: Freely available on the web at http://modorama.biocomputing.it/modalign. Website implemented in HTML and JavaScript with all major browsers supported. CONTACT: [email protected].
UR - http://hdl.handle.net/10754/596795
UR - https://academic.oup.com/bioinformatics/article-lookup/doi/10.1093/bioinformatics/bts070
UR - http://www.scopus.com/inward/record.url?scp=84859260956&partnerID=8YFLogxK
U2 - 10.1093/bioinformatics/bts070
DO - 10.1093/bioinformatics/bts070
M3 - Article
C2 - 22308148
SN - 1367-4803
VL - 28
SP - 1038
EP - 1039
JO - Bioinformatics
JF - Bioinformatics
IS - 7
ER -