TY - JOUR
T1 - Iridium-Catalyzed Reductive Amination of Levulinic Acid to Pyrrolidinones under H2 in Water
AU - Xu, Zhanwei
AU - Yan, Peifang
AU - Jiang, Hong
AU - Liu, Kairui
AU - Zhang, Z. Conrad
N1 - Generated from Scopus record by KAUST IRTS on 2023-10-22
PY - 2017/5/1
Y1 - 2017/5/1
N2 - The synthesis of pyrrolidinones from reductive amination of levulinic acid (LA) with primary amines is reported. Pyrrolidinones have various applications such as surfactants, pharmaceutical intermediates, dispersants, and solvents. The half-sandwich Cp*Ir complex (Cp* is 1,2,3,4,5-pentamethylcyclopenta-1,3-diene) coordinated by bipyridine ligand bearing both dimethylamino and ortho-hydroxyl groups showed high catalytic activity for the reductive amination of LA. A range of primary amines, such as aromatic and benzyl amines, were readily converted to corresponding pyrrolidinones in good yields.
AB - The synthesis of pyrrolidinones from reductive amination of levulinic acid (LA) with primary amines is reported. Pyrrolidinones have various applications such as surfactants, pharmaceutical intermediates, dispersants, and solvents. The half-sandwich Cp*Ir complex (Cp* is 1,2,3,4,5-pentamethylcyclopenta-1,3-diene) coordinated by bipyridine ligand bearing both dimethylamino and ortho-hydroxyl groups showed high catalytic activity for the reductive amination of LA. A range of primary amines, such as aromatic and benzyl amines, were readily converted to corresponding pyrrolidinones in good yields.
UR - https://onlinelibrary.wiley.com/doi/10.1002/cjoc.201600726
UR - http://www.scopus.com/inward/record.url?scp=85017152809&partnerID=8YFLogxK
U2 - 10.1002/cjoc.201600726
DO - 10.1002/cjoc.201600726
M3 - Article
SN - 1614-7065
VL - 35
SP - 581
EP - 585
JO - Chinese Journal of Chemistry
JF - Chinese Journal of Chemistry
IS - 5
ER -