Iron-catalysed sequential reaction towards α-aminonitriles from secondary amines, primary alcohols and trimethylsilyl cyanide

Hang Shen, Liangzhen Hu, Qing Liu, Muhammad Ijaz Hussain, Jing Pan, Mingming Huang, Yan Xiong

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

We have developed a one-pot iron-catalysed sequential reaction of secondary amines with primary alcohols, trimethylsilyl cyanide and TBHP under mild reaction conditions to give the corresponding α-aminonitriles.
Original languageEnglish (US)
Pages (from-to)2776-2779
Number of pages4
JournalCHEMICAL COMMUNICATIONS
Volume52
Issue number13
DOIs
StatePublished - Jan 1 2016
Externally publishedYes

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