Highly monodisperse, heterobifunctional poly(ethylene glycol) (PEG) was prepared by iterative chain extension of a PEGylated homostar using an octagol (EG8) building block to give MeO-EG24-OH in high purity. The branched structure facilitated purification of intermediates by chromatography, and mono-functionalization of the chain termini. This approach should be extendable to other classes of oligomers.
|Original language||English (US)|
|Number of pages||4|
|State||Published - Feb 7 2014|
ASJC Scopus subject areas
- Biomedical Engineering
- Polymers and Plastics
- Organic Chemistry