Low-Voltage Low-Noise High-CMRR Biopotential Integrated Preamplifier

Carolina Cabrera, Renzo Caballero, María Cecilia Costa-Rauschert, Conrado Rossi-Aicardi, Julián Oreggioni

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


This work presents a novel amplifier architecture which is the input stage of an analog front end targeting the acquisition of biological signals with low voltage supply (1.2 V), low noise, high Common Mode Rejection Ratio (CMRR) and high current efficiency. A prototype, designed and fabricated in a 130 nm CMOS technology, was characterized by simulations and measurements. Our preamplifier presents one of the lowest noise levels reported up-to-date (over the considered bandwidth) while presenting a very competitive performance in other important features. Results from measurements show a bandwidth from 20 Hz to 11 kHz, a CMRR higher than 70 dB, an equivalent input-referred noise as low as 1.3 μVrms. The Noise Efficiency Factor (NEF) at 2.5 and Power Efficiency Factor (PEF) at 7.5 are remarkable results.
Original languageEnglish (US)
Pages (from-to)1-10
Number of pages10
JournalIEEE Transactions on Circuits and Systems I: Regular Papers
StatePublished - 2020


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