Lysozyme fibrillation induced by convective flow under quasi contact-free conditions

Angelo Accardo, Manfred Burghammer, Emanuela Di Cola, Michael Reynolds, Enzo Di Fabrizio, Christian Riekel*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

The evaporation of a lysozyme solution drop containing Ca 2+ ions on a superhydrophobic poly(methyl methacrylate) surface was probed by X-ray microbeam raster-diffraction. We observe the rapid deposition of fibrillar lysozyme with amyloidic cross-β structure at the interface of the drop with the substrate under conditions of weak acidity, close to physiological.

Original languageEnglish (US)
Pages (from-to)6792-6796
Number of pages5
JournalSoft matter
Volume7
Issue number15
DOIs
StatePublished - Aug 7 2011
Externally publishedYes

ASJC Scopus subject areas

  • General Chemistry
  • Condensed Matter Physics

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