TY - JOUR
T1 - Machine assisted reaction optimization: A self-optimizing reactor system for continuous-flow photochemical reactions
AU - Poscharny, K.
AU - Fabry, D.C.
AU - Heddrich, S.
AU - Sugiono, E.
AU - Liauw, M.A.
AU - Rueping, Magnus
N1 - KAUST Repository Item: Exported on 2020-04-23
Acknowledgements: Technical assistance by Cornelia Vermeeren is very gratefully acknowledged. The research leading to these results has received funding from the European Research Council under the European Union's Seventh Framework Programme (FP/2007–2013)/ERC Grant Agreement No. 617044 (SunCatChem).
PY - 2018/4/7
Y1 - 2018/4/7
N2 - A methodology for the synthesis of oxetanes from benzophenone and furan derivatives is presented. UV-light irradiation in batch and flow systems allowed the [2 + 2] cycloaddition reaction to proceed and a broad range of oxetanes could be synthesized in manual and automated fashion. The identification of high-yielding reaction parameters was achieved through a new self-optimizing photoreactor system.
AB - A methodology for the synthesis of oxetanes from benzophenone and furan derivatives is presented. UV-light irradiation in batch and flow systems allowed the [2 + 2] cycloaddition reaction to proceed and a broad range of oxetanes could be synthesized in manual and automated fashion. The identification of high-yielding reaction parameters was achieved through a new self-optimizing photoreactor system.
UR - http://hdl.handle.net/10754/627521
UR - http://www.sciencedirect.com/science/article/pii/S0040402018303983
UR - http://www.scopus.com/inward/record.url?scp=85046121703&partnerID=8YFLogxK
U2 - 10.1016/j.tet.2018.04.019
DO - 10.1016/j.tet.2018.04.019
M3 - Article
AN - SCOPUS:85046121703
SN - 0040-4020
VL - 74
SP - 3171
EP - 3175
JO - Tetrahedron
JF - Tetrahedron
IS - 25
ER -