@article{3dbeaab05f894a848ae104b46823918c,
title = "Manganese-Catalyzed Regioselective Dehydrogenative C- versus N-Alkylation Enabled by a Solvent Switch: Experiment and Computation",
abstract = "The first base metal-catalyzed regioselective dehydrogenative alkylation of indolines using readily available alcohols as the alkylating reagent is reported. A single air- and moisture-stable manganese catalyst provides access to either C3- or N-alkylated indoles depending on the solvent used. Mechanistic studies indicate that the reaction takes place through a combined acceptorless dehydrogenation and hydrogen autotransfer strategy.",
author = "Borghs, {Jannik C.} and Viktoriia Zubar and {Azofra Mesa}, Luis and Jan Sklyaruk and Magnus Rueping",
note = "KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: This work was financially supported by the King Abdullah University of Science and Technology (KAUST), Saudi Arabia, Office of Sponsored Research (FCC/1/1974). We thank KAUST Supercomputing Laboratory for use of the supercomputer Shaheen II and providing the computational resources.",
year = "2020",
month = may,
day = "13",
doi = "10.1021/acs.orglett.0c01270",
language = "English (US)",
journal = "Organic Letters",
issn = "1523-7060",
publisher = "American Chemical Society",
}