Abstract
Arabs represent 5% of the world population and have a high prevalence of common disease, yet remain greatly underrepresented in genome-wide association studies, where only 1 in 600 individuals are Arab. We highlight the persistent and unaddressed underrepresentation of Arabs in genomic databases and discuss its impact on public health genomics and missed opportunities for biological discovery.
Original language | English (US) |
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Article number | 99 |
Journal | Genome medicine |
Volume | 15 |
Issue number | 1 |
DOIs |
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State | Published - Dec 2023 |
Keywords
- Arab
- Diversity
- Genomic
- GWAS
- Middle East
- Polygenic score
- Underrepresentation
ASJC Scopus subject areas
- Molecular Medicine
- Molecular Biology
- Genetics
- Genetics(clinical)