Metabolic exit from naive pluripotency

Jun Wu*, Juan Carlos Izpisua Belmonte

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Spatiotemporally distinct pluripotent states captured in vitro provide an accessible way of modelling early human development. An intricate interplay between the metabolome and histone modifications is now shown to drive the metabolic switch from human naive to primed pluripotency, one of the earliest steps of embryogenesis.

Original languageEnglish (US)
Pages (from-to)1519-1521
Number of pages3
JournalNature Cell Biology
Issue number12
StatePublished - Nov 27 2015

ASJC Scopus subject areas

  • Cell Biology


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