Metabolic gene expression changes in astrocytes in Multiple Sclerosis cerebral cortex are indicative of immune-mediated signaling

Keyphrases

• Astrocyte Culture 8%
• Brain Dysfunction 8%
• Central Nervous System 8%
• Cerebral Cortex 100%
• Cognitive Dysfunction 8%
• Connexin 43 (Cx43) 8%
• Cortical Brain 8%
• Differential Gene Expression Analysis 8%
• Gene Signature 8%
• Gray Matter Abnormality 8%
• Gray Matter Volume 83%
• IL-1 Signaling 8%
• Immune Stimuli 8%
• Immune-mediated 100%
• Immunohistochemical Analysis 8%
• Inflammasome 16%
• Inflammasome Activation 8%
• Interleukin-1β 33%
• Lactate Shuttle 58%
• Metabolic Gene Expression 100%
• Molecular Alterations 8%
• Mouse in Vivo 8%
• Multiple Sclerosis 100%
• Multiple Sclerosis Treatment 16%
• Neurological Dysfunction 8%
• Peripheral Immune Cells 16%
• Seizure 8%
• Signal Process 8%
• Specific Genes 8%

Neuroscience

• Adenosine Triphosphate 14%
• Astrocyte 100%
• Central Nervous System 7%
• Cognitive Disorders 7%
• Expression Analysis 7%
• Gene Control 7%
• Gene Expression 100%
• Gray Matter 78%
• IL1B 14%
• In Vitro 14%
• In Vivo 7%
• Inflammasome 21%
• Lactate Shuttle 50%
• Multiple Sclerosis 100%