Metagenomics of Imported Multidrug-Resistant Mycobacterium leprae, Saudi Arabia, 2017

Qingtian Guan; Talal S. Almutairi; Tahani Alhalouli; Arnab Pain; Faisal Alasmari

doi:10.3201/eid2603.190661

Metagenomics of Imported Multidrug-Resistant Mycobacterium leprae, Saudi Arabia, 2017

Qingtian Guan, Talal S. Almutairi, Tahani Alhalouli, Arnab Pain, Faisal Alasmari

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3 Scopus citations

Abstract

Using shotgun metagenomics, we identified an imported case of multidrug-resistant Mycobacterium leprae in a Filipino resident of Saudi Arabia in 2017. We determined the phylogenomic lineage (3K1) and identified mutations in rpoB and rrs corresponding to the multidrug-resistance phenotype clinically observed. Metagenomics sequencing can be used to identify multidrug-resistant M. leprae.

Original language	English (US)
Pages (from-to)	615-617
Number of pages	3
Journal	Emerging Infectious Diseases
Volume	26
Issue number	3
DOIs	https://doi.org/10.3201/eid2603.190661
State	Published - Feb 4 2020

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10.3201/eid2603.190661

https://repository.kaust.edu.sa/bitstream/10754/661704/1/19-0661%20%281%29.pdf

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abstract = "Using shotgun metagenomics, we identified an imported case of multidrug-resistant Mycobacterium leprae in a Filipino resident of Saudi Arabia in 2017. We determined the phylogenomic lineage (3K1) and identified mutations in rpoB and rrs corresponding to the multidrug-resistance phenotype clinically observed. Metagenomics sequencing can be used to identify multidrug-resistant M. leprae.",

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AU - Almutairi, Talal S.

AU - Alhalouli, Tahani

AU - Pain, Arnab

AU - Alasmari, Faisal

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PY - 2020/2/4

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AB - Using shotgun metagenomics, we identified an imported case of multidrug-resistant Mycobacterium leprae in a Filipino resident of Saudi Arabia in 2017. We determined the phylogenomic lineage (3K1) and identified mutations in rpoB and rrs corresponding to the multidrug-resistance phenotype clinically observed. Metagenomics sequencing can be used to identify multidrug-resistant M. leprae.

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ER -

Metagenomics of Imported Multidrug-Resistant Mycobacterium leprae, Saudi Arabia, 2017

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