TY - JOUR
T1 - Metal-Organic Frameworks Meet Molecularly Imprinted Polymers
T2 - Insights and Prospects for Sensor Applications
AU - Lahcen, Abdellatif Ait
AU - Surya, Sandeep G.
AU - Beduk, Tutku
AU - Vijjapu, Mani Teja
AU - Lamaoui, Abderrahman
AU - Durmus, Ceren
AU - Timur, Suna
AU - Shekhah, Osama
AU - Mani, Veerappan
AU - Amine, Aziz
AU - Eddaoudi, Mohamed
AU - Salama, Khaled Nabil
N1 - Funding Information:
The authors would like to acknowledge the financial support in the form of funding from King Abdullah University of Science and Technology (KAUST), Saudi Arabia. Furthermore, we thank the KAUST Sensor Initiative and KAUST visiting student program for supporting this work.
Publisher Copyright:
© 2022 The Authors. Published by American Chemical Society.
PY - 2022
Y1 - 2022
N2 - The use of porous materials as the core for synthesizing molecularly imprinted polymers (MIPs) adds significant value to the resulting sensing system. This review covers in detail the current progress and achievements regarding the synergistic combination of MIPs and porous materials, namely metal/covalent-organic frameworks (MOFs/COFs), including the application of such frameworks in the development of upgraded sensor platforms. The different processes involved in the synthesis of MOF/COF-MIPs are outlined, along with their intrinsic properties. Special attention is paid to debriefing the impact of the morphological changes that occur through the synergistic combination compared to those that occur due to the individual entities. Thereafter, the strategies used for building the sensors, as well as the transduction modes, are overviewed and discussed. This is followed by a full description of research advances for various types of MOF/COF-MIP-based (bio)sensors and their applications in the fields of environmental monitoring, food safety, and pharmaceutical analysis. Finally, the challenges/drawbacks, as well as the prospects of this research field, are discussed in detail.
AB - The use of porous materials as the core for synthesizing molecularly imprinted polymers (MIPs) adds significant value to the resulting sensing system. This review covers in detail the current progress and achievements regarding the synergistic combination of MIPs and porous materials, namely metal/covalent-organic frameworks (MOFs/COFs), including the application of such frameworks in the development of upgraded sensor platforms. The different processes involved in the synthesis of MOF/COF-MIPs are outlined, along with their intrinsic properties. Special attention is paid to debriefing the impact of the morphological changes that occur through the synergistic combination compared to those that occur due to the individual entities. Thereafter, the strategies used for building the sensors, as well as the transduction modes, are overviewed and discussed. This is followed by a full description of research advances for various types of MOF/COF-MIP-based (bio)sensors and their applications in the fields of environmental monitoring, food safety, and pharmaceutical analysis. Finally, the challenges/drawbacks, as well as the prospects of this research field, are discussed in detail.
KW - biosensors
KW - chemical sensors
KW - covalent-organic frameworks
KW - metal-organic frameworks
KW - molecularly imprinted polymers
KW - solid-phase extraction
UR - http://www.scopus.com/inward/record.url?scp=85141552375&partnerID=8YFLogxK
U2 - 10.1021/acsami.2c12842
DO - 10.1021/acsami.2c12842
M3 - Review article
C2 - 36315467
AN - SCOPUS:85141552375
SN - 1944-8244
VL - 14
SP - 49399
EP - 49424
JO - ACS Applied Materials and Interfaces
JF - ACS Applied Materials and Interfaces
IS - 44
ER -