Microalbuminuria determination on a microchip with fluorescence detection based on thin-film organic light emitting diodes

O. Hofmann; X. Wang; J. C. DeMello; D. D.C. Bradley; A. J. DeMello

Microalbuminuria determination on a microchip with fluorescence detection based on thin-film organic light emitting diodes

O. Hofmann, X. Wang, J. C. DeMello, D. D.C. Bradley, A. J. DeMello

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

As a first step towards a disposable diagnostic microchip for determination of urinary human serum albumin (HSA), we report the use of a thin-film organic light emitting diode (OLED) as an excitation source for microscale fluorescence detection. The OLED has a peak emission at 540 nm, is simple to fabricate and operates at drive voltages below 10 V. In a PDMS microchip, HSA was reacted with Albumin Blue 580, generating a strong emission at 620 nm when excited with the OLED. HSA concentrations down to 10 mg/L could be detected, enabling the determination of microalbuminuria (MAU), an increased urinary albumin excretion indicative of renal disease. Copyright © 2005 by the Transducer Research Foundation, Inc.

Original language	English (US)
Title of host publication	Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Publisher	Transducer Research [email protected]
ISBN (Print)	0974361119
State	Published - Jan 1 2005
Externally published	Yes

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Hofmann, O., Wang, X., DeMello, J. C., Bradley, D. D. C., & DeMello, A. J. (2005). Microalbuminuria determination on a microchip with fluorescence detection based on thin-film organic light emitting diodes. In Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences Transducer Research [email protected].

Hofmann, O. ; Wang, X. ; DeMello, J. C. et al. / Microalbuminuria determination on a microchip with fluorescence detection based on thin-film organic light emitting diodes. Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Transducer Research [email protected], 2005.

@inproceedings{9108aaf66cde474cb523a492abaa2f10,

title = "Microalbuminuria determination on a microchip with fluorescence detection based on thin-film organic light emitting diodes",

abstract = "As a first step towards a disposable diagnostic microchip for determination of urinary human serum albumin (HSA), we report the use of a thin-film organic light emitting diode (OLED) as an excitation source for microscale fluorescence detection. The OLED has a peak emission at 540 nm, is simple to fabricate and operates at drive voltages below 10 V. In a PDMS microchip, HSA was reacted with Albumin Blue 580, generating a strong emission at 620 nm when excited with the OLED. HSA concentrations down to 10 mg/L could be detected, enabling the determination of microalbuminuria (MAU), an increased urinary albumin excretion indicative of renal disease. Copyright {\textcopyright} 2005 by the Transducer Research Foundation, Inc.",

author = "O. Hofmann and X. Wang and DeMello, {J. C.} and Bradley, {D. D.C.} and DeMello, {A. J.}",

note = "Generated from Scopus record by KAUST IRTS on 2019-11-27",

year = "2005",

month = jan,

day = "1",

language = "English (US)",

isbn = "0974361119",

booktitle = "Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences",

publisher = "Transducer Research [email protected]",

}

Hofmann, O, Wang, X, DeMello, JC, Bradley, DDC & DeMello, AJ 2005, Microalbuminuria determination on a microchip with fluorescence detection based on thin-film organic light emitting diodes. in Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Transducer Research [email protected].

Microalbuminuria determination on a microchip with fluorescence detection based on thin-film organic light emitting diodes. / Hofmann, O.; Wang, X.; DeMello, J. C. et al.
Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Transducer Research [email protected], 2005.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Microalbuminuria determination on a microchip with fluorescence detection based on thin-film organic light emitting diodes

AU - Hofmann, O.

AU - Wang, X.

AU - DeMello, J. C.

AU - Bradley, D. D.C.

AU - DeMello, A. J.

N1 - Generated from Scopus record by KAUST IRTS on 2019-11-27

PY - 2005/1/1

Y1 - 2005/1/1

N2 - As a first step towards a disposable diagnostic microchip for determination of urinary human serum albumin (HSA), we report the use of a thin-film organic light emitting diode (OLED) as an excitation source for microscale fluorescence detection. The OLED has a peak emission at 540 nm, is simple to fabricate and operates at drive voltages below 10 V. In a PDMS microchip, HSA was reacted with Albumin Blue 580, generating a strong emission at 620 nm when excited with the OLED. HSA concentrations down to 10 mg/L could be detected, enabling the determination of microalbuminuria (MAU), an increased urinary albumin excretion indicative of renal disease. Copyright © 2005 by the Transducer Research Foundation, Inc.

AB - As a first step towards a disposable diagnostic microchip for determination of urinary human serum albumin (HSA), we report the use of a thin-film organic light emitting diode (OLED) as an excitation source for microscale fluorescence detection. The OLED has a peak emission at 540 nm, is simple to fabricate and operates at drive voltages below 10 V. In a PDMS microchip, HSA was reacted with Albumin Blue 580, generating a strong emission at 620 nm when excited with the OLED. HSA concentrations down to 10 mg/L could be detected, enabling the determination of microalbuminuria (MAU), an increased urinary albumin excretion indicative of renal disease. Copyright © 2005 by the Transducer Research Foundation, Inc.

UR - http://www.scopus.com/inward/record.url?scp=84902489773&partnerID=8YFLogxK

M3 - Conference contribution

SN - 0974361119

BT - Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences

PB - Transducer Research [email protected]

ER -

Hofmann O, Wang X, DeMello JC, Bradley DDC, DeMello AJ. Microalbuminuria determination on a microchip with fluorescence detection based on thin-film organic light emitting diodes. In Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Transducer Research [email protected]. 2005

Microalbuminuria determination on a microchip with fluorescence detection based on thin-film organic light emitting diodes

Abstract

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