Monodisperse polymer beads as packing material for high‐performance liquid chromatography. Synthesis and properties of monidisperse polystyrene and poly(methacrylate) latex seeds

Vladmír S̆migol; Frantis̆ek S̆vec; Ken Hosoya; Qing Wang; Jean M.J. Fréchet

doi:10.1002/apmc.1992.051950112

Monodisperse polymer beads as packing material for high‐performance liquid chromatography. Synthesis and properties of monidisperse polystyrene and poly(methacrylate) latex seeds

Vladmír S̆migol, Frantis̆ek S̆vec^*, Ken Hosoya, Qing Wang, Jean M.J. Fréchet

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

134 Scopus citations

Abstract

The effects of initiator concentration, ionic strength of polymerization medium, polymerization temperature, and monomer/water phase ratio on particle size, particle size distribution and molecular weight of the resulting polymers prepared by an emulsifier‐free emulsion polymerization of styrene, methyl methacrylate and glycidyl methacrylate have been studied. Optimal conditions for preparation of uniformly sized polystyrene particles larger than 1 μm have been found. An attempt to synthesize monodisperse particles of similar size from methacrylate monomers and crosslinked particles has failed. It is shown that the swelling ability of “non‐activated” latex particles does not exceed 70 fold increase in the volume and strongly depends on the size of the original particles.

Original language	English (US)
Pages (from-to)	151-164
Number of pages	14
Journal	Die Angewandte Makromolekulare Chemie
Volume	195
Issue number	1
DOIs	https://doi.org/10.1002/apmc.1992.051950112
State	Published - Feb 1992
Externally published	Yes

ASJC Scopus subject areas

General Materials Science

Access to Document

10.1002/apmc.1992.051950112

Cite this

@article{3f5defc7ccbe43a88ee2f423c9e0f1bd,

title = "Monodisperse polymer beads as packing material for high‐performance liquid chromatography. Synthesis and properties of monidisperse polystyrene and poly(methacrylate) latex seeds",

abstract = "The effects of initiator concentration, ionic strength of polymerization medium, polymerization temperature, and monomer/water phase ratio on particle size, particle size distribution and molecular weight of the resulting polymers prepared by an emulsifier‐free emulsion polymerization of styrene, methyl methacrylate and glycidyl methacrylate have been studied. Optimal conditions for preparation of uniformly sized polystyrene particles larger than 1 μm have been found. An attempt to synthesize monodisperse particles of similar size from methacrylate monomers and crosslinked particles has failed. It is shown that the swelling ability of “non‐activated” latex particles does not exceed 70 fold increase in the volume and strongly depends on the size of the original particles.",

author = "Vladm{\'i}r {\u S}migol and Franti{\u s}ek {\u S}vec and Ken Hosoya and Qing Wang and Fr{\'e}chet, {Jean M.J.}",

year = "1992",

month = feb,

doi = "10.1002/apmc.1992.051950112",

language = "English (US)",

volume = "195",

pages = "151--164",

journal = "Die Angewandte Makromolekulare Chemie",

issn = "0003-3146",

publisher = "Wiley-VCH Verlag",

number = "1",

}

Monodisperse polymer beads as packing material for high‐performance liquid chromatography. Synthesis and properties of monidisperse polystyrene and poly(methacrylate) latex seeds. / S̆migol, Vladmír; S̆vec, Frantis̆ek; Hosoya, Ken et al.
In: Die Angewandte Makromolekulare Chemie, Vol. 195, No. 1, 02.1992, p. 151-164.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Monodisperse polymer beads as packing material for high‐performance liquid chromatography. Synthesis and properties of monidisperse polystyrene and poly(methacrylate) latex seeds

AU - S̆migol, Vladmír

AU - S̆vec, Frantis̆ek

AU - Hosoya, Ken

AU - Wang, Qing

AU - Fréchet, Jean M.J.

PY - 1992/2

Y1 - 1992/2

N2 - The effects of initiator concentration, ionic strength of polymerization medium, polymerization temperature, and monomer/water phase ratio on particle size, particle size distribution and molecular weight of the resulting polymers prepared by an emulsifier‐free emulsion polymerization of styrene, methyl methacrylate and glycidyl methacrylate have been studied. Optimal conditions for preparation of uniformly sized polystyrene particles larger than 1 μm have been found. An attempt to synthesize monodisperse particles of similar size from methacrylate monomers and crosslinked particles has failed. It is shown that the swelling ability of “non‐activated” latex particles does not exceed 70 fold increase in the volume and strongly depends on the size of the original particles.

AB - The effects of initiator concentration, ionic strength of polymerization medium, polymerization temperature, and monomer/water phase ratio on particle size, particle size distribution and molecular weight of the resulting polymers prepared by an emulsifier‐free emulsion polymerization of styrene, methyl methacrylate and glycidyl methacrylate have been studied. Optimal conditions for preparation of uniformly sized polystyrene particles larger than 1 μm have been found. An attempt to synthesize monodisperse particles of similar size from methacrylate monomers and crosslinked particles has failed. It is shown that the swelling ability of “non‐activated” latex particles does not exceed 70 fold increase in the volume and strongly depends on the size of the original particles.

UR - http://www.scopus.com/inward/record.url?scp=84985561016&partnerID=8YFLogxK

U2 - 10.1002/apmc.1992.051950112

DO - 10.1002/apmc.1992.051950112

M3 - Article

AN - SCOPUS:84985561016

SN - 0003-3146

VL - 195

SP - 151

EP - 164

JO - Die Angewandte Makromolekulare Chemie

JF - Die Angewandte Makromolekulare Chemie

IS - 1

ER -

Monodisperse polymer beads as packing material for high‐performance liquid chromatography. Synthesis and properties of monidisperse polystyrene and poly(methacrylate) latex seeds

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this