@article{c351185006674b8b908d1ae8c690972d,
title = "N-Heterocyclic Carbene-Catalyzed Vinylogous Mukaiyama Aldol Reaction of α-Keto Esters and α-Trifluoromethyl Ketones",
abstract = "{\textcopyright} Georg Thieme Verlag Stuttgart · New York · Synthesis 2016. N-Heterocyclic carbene (NHC)-catalyzed vinylogous Mukaiyama aldol reaction of ketones was developed. Under the catalysis of 5 mol% NHC, α-keto esters and α-trifluoromethyl ketones reacted with 2-(trimethysilyloxy)furan efficiently to produce γ-substituted butenolides containing adjacent quaternary and tertiary carbon centers in high yields with good diastereoselectivities.",
author = "Guang-Fen Du and Ying Wang and Fen Xing and Mei Xue and Xu-Hong Guo and Kuo-Wei Huang and Bin Dai",
note = "KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: This work was supported by the National Natural Science Foundation of China (Nos. 21262027, 21428302) and Shihezi University (No. 2012ZRKXJQ06). We thank Dr. L. He of Shihezi University for helpful discussions.",
year = "2015",
month = nov,
day = "4",
doi = "10.1055/s-0035-1560833",
language = "English (US)",
volume = "48",
pages = "79--84",
journal = "Synthesis",
issn = "0039-7881",
publisher = "Thieme Gruppe",
number = "01",
}