NAD+ depletion and defense in bacteria

Meng Wang, Qing Ji*, Peng Liu, Yukun Liu

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

7 Scopus citations


Depletion of nicotinamide adenine dinucleotide (NAD+), an important regulator of cellular energy metabolism, is a common strategy in immune-mediated cell death (ICD) in both prokaryotes and eukaryotes. Recent studies have revealed how bacteria use NAD+ depletion to protect against phages, providing insight into how eukaryotic ICD might have evolved.

Original languageEnglish (US)
Pages (from-to)435-438
Number of pages4
JournalTrends in Microbiology
Issue number5
StatePublished - May 2023

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)
  • Virology
  • Infectious Diseases


Dive into the research topics of 'NAD+ depletion and defense in bacteria'. Together they form a unique fingerprint.

Cite this