Abstract
Depletion of nicotinamide adenine dinucleotide (NAD+), an important regulator of cellular energy metabolism, is a common strategy in immune-mediated cell death (ICD) in both prokaryotes and eukaryotes. Recent studies have revealed how bacteria use NAD+ depletion to protect against phages, providing insight into how eukaryotic ICD might have evolved.
Original language | English (US) |
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Pages (from-to) | 435-438 |
Number of pages | 4 |
Journal | Trends in Microbiology |
Volume | 31 |
Issue number | 5 |
DOIs | |
State | Published - May 2023 |
ASJC Scopus subject areas
- Microbiology
- Microbiology (medical)
- Virology
- Infectious Diseases