TY - CHAP
T1 - Nano-particles for biomedical applications
AU - Decuzzi, Paolo
AU - Coclite, Alessandro
AU - Lee, Aeju
AU - Palange, Anna Lisa
AU - Di Mascolo, Daniele
AU - Chiappini, Ciro
AU - Santos, Hélder A.
AU - Coluccio, Maria Laura
AU - Perozziello, Gerardo
AU - Candeloro, Patrizio
AU - Di Fabrizio, Enzo M.
AU - Gentile, Francesco
N1 - KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: Dr. Hélder A. Santos acknowledges the Academy of Finland (project numbers 252215 and 281300), the University of Helsinki and the European Research Council under the European Union's Seventh Framework Programme (FP7/2007-2013)/ERC Grant agreement number 310892 for financial support. Dr. Dongfei Liu and Dr. Bárbara Herranz Blanco (Division of Pharmaceutical Chemistry and Technology) are also acknowledged for their discussions and for providing some of the material in the microfluidics section. Professor Francesco Gentile acknowledges the Italian Minister of Health (Project number GR-2010-2320665).
PY - 2017/11/6
Y1 - 2017/11/6
N2 - Nanoparticles (NPnanoparticle (NP)s) are extremely small particulates with an average size that ranges from a micron or less to a few nanometers. The large majority of NPs necessitate nanotechnology methods for their production. The size of NPs may vary over a significant range, which underlies their scientific potential in that NPs may help cross the bridge between bulk materials and molecular structures. More importantly, NPs are (nano)tech products and thus, in contrast to natural systems, they can be designed and engineered. On directly interacting with cells, including the structures of cells, their machinery and their waste products, NPs represent an unprecedented tool for addressing specific biological problems. In this chapter, we will briefly review some recent advances in nanoparticle research for biomedical applications, ranging from mesoporous silicon particles to gold and silver nanoparticles and polymeric nanocarriers for therapeutic, diagnosis, or theranostic (therapeutics + diagnosis) applications. We will offer a description of how, at the current state of the art, similar nanomedicine platforms are realized.
AB - Nanoparticles (NPnanoparticle (NP)s) are extremely small particulates with an average size that ranges from a micron or less to a few nanometers. The large majority of NPs necessitate nanotechnology methods for their production. The size of NPs may vary over a significant range, which underlies their scientific potential in that NPs may help cross the bridge between bulk materials and molecular structures. More importantly, NPs are (nano)tech products and thus, in contrast to natural systems, they can be designed and engineered. On directly interacting with cells, including the structures of cells, their machinery and their waste products, NPs represent an unprecedented tool for addressing specific biological problems. In this chapter, we will briefly review some recent advances in nanoparticle research for biomedical applications, ranging from mesoporous silicon particles to gold and silver nanoparticles and polymeric nanocarriers for therapeutic, diagnosis, or theranostic (therapeutics + diagnosis) applications. We will offer a description of how, at the current state of the art, similar nanomedicine platforms are realized.
UR - http://hdl.handle.net/10754/660637
UR - http://link.springer.com/10.1007/978-3-662-54357-3_21
UR - http://www.scopus.com/inward/record.url?scp=85075954219&partnerID=8YFLogxK
U2 - 10.1007/978-3-662-54357-3_21
DO - 10.1007/978-3-662-54357-3_21
M3 - Chapter
SN - 9783662543559
SP - 643
EP - 691
BT - Springer Handbook of Nanotechnology
PB - Springer Berlin Heidelberg
ER -