Nickel-Catalyzed C sp2 –C sp3 Cross-Coupling via C–O Bond Activation

Lin Guo; Chien-Chi Hsiao; Huifeng Yue; Xiangqian Liu; Magnus Rueping

doi:10.1021/acscatal.6b00801

Nickel-Catalyzed C sp2 –C sp3 Cross-Coupling via C–O Bond Activation

Lin Guo, Chien-Chi Hsiao, Huifeng Yue, Xiangqian Liu, Magnus Rueping

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Abstract

A new and efficient nickel-catalyzed alkylation of CAr-O electrophiles with B-alkyl-9-BBNs is described. The transformation is characterized by its functional group tolerance and provides a practical and versatile access to various Csp2-Csp3 bonds through Csp2-O substitution, without the restriction of β-hydride elimination. Moreover, the advantage of the newly developed method was demonstrated in a selective and sequential C-O bond activation process. © 2016 American Chemical Society.

Original language	English (US)
Pages (from-to)	4438-4442
Number of pages	5
Journal	ACS Catalysis
Volume	6
Issue number	7
DOIs	https://doi.org/10.1021/acscatal.6b00801
State	Published - Jun 13 2016

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title = "Nickel-Catalyzed C sp2 –C sp3 Cross-Coupling via C–O Bond Activation",

abstract = "A new and efficient nickel-catalyzed alkylation of CAr-O electrophiles with B-alkyl-9-BBNs is described. The transformation is characterized by its functional group tolerance and provides a practical and versatile access to various Csp2-Csp3 bonds through Csp2-O substitution, without the restriction of β-hydride elimination. Moreover, the advantage of the newly developed method was demonstrated in a selective and sequential C-O bond activation process. {\textcopyright} 2016 American Chemical Society.",

author = "Lin Guo and Chien-Chi Hsiao and Huifeng Yue and Xiangqian Liu and Magnus Rueping",

note = "KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: L.G., H.Y., and X.L. gratefully acknowledge the China Scholarship Council. C.-C.H. gratefully acknowledges DAAD for fellowship.",

year = "2016",

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doi = "10.1021/acscatal.6b00801",

language = "English (US)",

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T1 - Nickel-Catalyzed C sp2 –C sp3 Cross-Coupling via C–O Bond Activation

AU - Guo, Lin

AU - Hsiao, Chien-Chi

AU - Yue, Huifeng

AU - Liu, Xiangqian

AU - Rueping, Magnus

N1 - KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: L.G., H.Y., and X.L. gratefully acknowledge the China Scholarship Council. C.-C.H. gratefully acknowledges DAAD for fellowship.

PY - 2016/6/13

Y1 - 2016/6/13

N2 - A new and efficient nickel-catalyzed alkylation of CAr-O electrophiles with B-alkyl-9-BBNs is described. The transformation is characterized by its functional group tolerance and provides a practical and versatile access to various Csp2-Csp3 bonds through Csp2-O substitution, without the restriction of β-hydride elimination. Moreover, the advantage of the newly developed method was demonstrated in a selective and sequential C-O bond activation process. © 2016 American Chemical Society.

AB - A new and efficient nickel-catalyzed alkylation of CAr-O electrophiles with B-alkyl-9-BBNs is described. The transformation is characterized by its functional group tolerance and provides a practical and versatile access to various Csp2-Csp3 bonds through Csp2-O substitution, without the restriction of β-hydride elimination. Moreover, the advantage of the newly developed method was demonstrated in a selective and sequential C-O bond activation process. © 2016 American Chemical Society.

UR - http://hdl.handle.net/10754/621676

UR - https://pubs.acs.org/doi/10.1021/acscatal.6b00801

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DO - 10.1021/acscatal.6b00801

M3 - Article

SN - 2155-5435

VL - 6

SP - 4438

EP - 4442

JO - ACS Catalysis

JF - ACS Catalysis

IS - 7

ER -

Nickel-Catalyzed C sp2 –C sp3 Cross-Coupling via C–O Bond Activation

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