Novel poly(amino ester)s obtained from Michael addition polymerizations of trifunctional amine monomers with diacrylates: Safe and efficient DNA carriers

Ye Liu; Decheng Wu; Yuexia Ma; Guping Tang; Shu Wang; Chaobin He; Taishung Chung; Suathong Goh

doi:10.1039/b309487a

Novel poly(amino ester)s obtained from Michael addition polymerizations of trifunctional amine monomers with diacrylates: Safe and efficient DNA carriers

Ye Liu^*, Decheng Wu, Yuexia Ma, Guping Tang, Shu Wang, Chaobin He, Taishung Chung, Suathong Goh

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

70 Scopus citations

Abstract

Novel biodegradable poly(amino ester)s containing secondary and tertiary amines in the backbones were obtained from the Michael addition polymerizations of trifunctional amine monomers with diacrylates, and showed high transfection efficiency for the delivery of DNA comparable to those of polyethylenimine (PEI) and low cytotoxicity.

Original language	English (US)
Pages (from-to)	2630-2631
Number of pages	2
Journal	CHEMICAL COMMUNICATIONS
Volume	3
Issue number	20
DOIs	https://doi.org/10.1039/b309487a
State	Published - 2003
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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title = "Novel poly(amino ester)s obtained from Michael addition polymerizations of trifunctional amine monomers with diacrylates: Safe and efficient DNA carriers",

abstract = "Novel biodegradable poly(amino ester)s containing secondary and tertiary amines in the backbones were obtained from the Michael addition polymerizations of trifunctional amine monomers with diacrylates, and showed high transfection efficiency for the delivery of DNA comparable to those of polyethylenimine (PEI) and low cytotoxicity.",

author = "Ye Liu and Decheng Wu and Yuexia Ma and Guping Tang and Shu Wang and Chaobin He and Taishung Chung and Suathong Goh",

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TY - JOUR

T1 - Novel poly(amino ester)s obtained from Michael addition polymerizations of trifunctional amine monomers with diacrylates

T2 - Safe and efficient DNA carriers

AU - Liu, Ye

AU - Wu, Decheng

AU - Ma, Yuexia

AU - Tang, Guping

AU - Wang, Shu

AU - He, Chaobin

AU - Chung, Taishung

AU - Goh, Suathong

PY - 2003

Y1 - 2003

N2 - Novel biodegradable poly(amino ester)s containing secondary and tertiary amines in the backbones were obtained from the Michael addition polymerizations of trifunctional amine monomers with diacrylates, and showed high transfection efficiency for the delivery of DNA comparable to those of polyethylenimine (PEI) and low cytotoxicity.

AB - Novel biodegradable poly(amino ester)s containing secondary and tertiary amines in the backbones were obtained from the Michael addition polymerizations of trifunctional amine monomers with diacrylates, and showed high transfection efficiency for the delivery of DNA comparable to those of polyethylenimine (PEI) and low cytotoxicity.

UR - http://www.scopus.com/inward/record.url?scp=0142094003&partnerID=8YFLogxK

U2 - 10.1039/b309487a

DO - 10.1039/b309487a

M3 - Article

AN - SCOPUS:0142094003

SN - 1359-7345

VL - 3

SP - 2630

EP - 2631

JO - CHEMICAL COMMUNICATIONS

JF - CHEMICAL COMMUNICATIONS

IS - 20

ER -

Novel poly(amino ester)s obtained from Michael addition polymerizations of trifunctional amine monomers with diacrylates: Safe and efficient DNA carriers

Abstract

ASJC Scopus subject areas

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