TY - JOUR
T1 - Nsite, NsiteH and NsiteM Computer Tools for Studying Tran-scription Regulatory Elements
AU - Shahmuradov, Ilham
AU - Solovyev, Victor
N1 - KAUST Repository Item: Exported on 2020-10-01
PY - 2015/7/2
Y1 - 2015/7/2
N2 - Summary: Gene transcription is mostly conducted through interactions of various transcription factors and their binding sites on DNA (regulatory elements, REs). Today, we are still far from understanding the real regulatory content of promoter regions. Computer methods for identification of REs remain a widely used tool for studying and understanding transcriptional regulation mechanisms. The Nsite, NsiteH and NsiteM programs perform searches for statistically significant (non-random) motifs of known human, animal and plant one-box and composite REs in a single genomic sequence, in a pair of aligned homologous sequences and in a set of functionally related sequences, respectively.
AB - Summary: Gene transcription is mostly conducted through interactions of various transcription factors and their binding sites on DNA (regulatory elements, REs). Today, we are still far from understanding the real regulatory content of promoter regions. Computer methods for identification of REs remain a widely used tool for studying and understanding transcriptional regulation mechanisms. The Nsite, NsiteH and NsiteM programs perform searches for statistically significant (non-random) motifs of known human, animal and plant one-box and composite REs in a single genomic sequence, in a pair of aligned homologous sequences and in a set of functionally related sequences, respectively.
UR - http://hdl.handle.net/10754/559100
UR - http://bioinformatics.oxfordjournals.org/lookup/doi/10.1093/bioinformatics/btv404
UR - http://www.scopus.com/inward/record.url?scp=84947580031&partnerID=8YFLogxK
U2 - 10.1093/bioinformatics/btv404
DO - 10.1093/bioinformatics/btv404
M3 - Article
C2 - 26142184
SN - 1367-4803
VL - 31
SP - 3544
EP - 3545
JO - Bioinformatics
JF - Bioinformatics
IS - 21
ER -