Numerical simulation of the stratum corneum's penetration property using finite element method

How could the outer substance penetrate through the skin lies on the stratum corneum, because it is the main barrier in the multi-layers of the skin. In this work, supposing the keratin cell with a special geometry as Tetrakaidecahedron, the discretization of the stratum corneum region was given at first in two steps: 1. The discretization of the keratin cell; 2. The discretization of fattiness that surrounds the keratin. Then numerical simulation was performed using finite element method and the multi-grid method. The former was to obtain the discretization of basic elements, the latter was to decrease the high frequency error. A visualization of the numerical simulation was shown in the paper.