Abstract
Partial differential equations describing the dynamics of cell population densities from a fluid mechanical perspective can model the growth of avascular tumours. In this framework, we consider a system of equations that describes the interaction between a population of dividing cells and a population of non-dividing cells. The two cell populations are characterised by different mobilities. We present the results of numerical simulations displaying two-dimensional spherical waves with sharp interfaces between dividing and non-dividing cells. Furthermore, we numerically observe how different ratios between the mobilities change the morphology of the interfaces, and lead to the emergence of finger-like patterns of invasion above a threshold. Motivated by these simulations, we study the existence of one-dimensional travelling wave solutions.
Original language | English (US) |
---|---|
Pages (from-to) | 299-311 |
Number of pages | 13 |
Journal | Kinetic and Related Models |
Volume | 10 |
Issue number | 1 |
DOIs | |
State | Published - Nov 18 2016 |