TY - GEN
T1 - Operation mechanism of n-type organic electronic metabolite sensors
AU - Druet, Victor
AU - Nayak, Prem
AU - Ohayon, David
AU - Koklu, Anil
AU - Inal, Sahika
AU - Chen, Xingxing
AU - Moser, Maximilian
AU - McCulloch, Iain
N1 - KAUST Repository Item: Exported on 2022-03-17
PY - 2022/2/7
Y1 - 2022/2/7
N2 - When combined with oxidase enzymes, the NDI-T2 based electron transporting (n-type) polymer led to high performance metabolite sensors, yet their working mechanism has been poorly understood.[1], [2] By monitoring oxygen, hydrogen peroxide, and pH changes in the electrolyte surrounding the n-type channel and gate as well as the potential of each electrical contact in the transistor, we shed light on the catalytic events occurring at the polymer-enzyme interface. We show that in its doped sate, the n-type film performs oxygen reduction reaction and that the n-OECT characteristics are sensitive to oxygen. We find a correlation between the amount of dissolved oxygen and the n-OECT sensor current generated during the metabolite oxidation and that using the n-type polymer at the gate electrode is critical for sensor operation. Our results show the importance of in operando analysis for understanding polymer-catalytic enzyme activity, as well as the importance of ambient oxygen in the operation of n-type devices.
AB - When combined with oxidase enzymes, the NDI-T2 based electron transporting (n-type) polymer led to high performance metabolite sensors, yet their working mechanism has been poorly understood.[1], [2] By monitoring oxygen, hydrogen peroxide, and pH changes in the electrolyte surrounding the n-type channel and gate as well as the potential of each electrical contact in the transistor, we shed light on the catalytic events occurring at the polymer-enzyme interface. We show that in its doped sate, the n-type film performs oxygen reduction reaction and that the n-OECT characteristics are sensitive to oxygen. We find a correlation between the amount of dissolved oxygen and the n-OECT sensor current generated during the metabolite oxidation and that using the n-type polymer at the gate electrode is critical for sensor operation. Our results show the importance of in operando analysis for understanding polymer-catalytic enzyme activity, as well as the importance of ambient oxygen in the operation of n-type devices.
UR - http://hdl.handle.net/10754/675855
UR - https://www.nanoge.org/proceedings/NSM22/61dbf26f55c0d04974d5b8fc
U2 - 10.29363/nanoge.nsm.2022.314
DO - 10.29363/nanoge.nsm.2022.314
M3 - Conference contribution
BT - Proceedings of the nanoGe Spring Meeting 2022
PB - Fundació Scito
ER -