TY - JOUR
T1 - Palladium supported on natural phosphate: Catalyst for Suzuki coupling reactions in water
AU - Hassine, Ayoub
AU - Sebti, Said
AU - Solhy, Abderrahim
AU - Zahouily, Mohamed
AU - Len, Christophe
AU - Hedhili, Mohamed N.
AU - Fihri, Aziz
N1 - KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: Thanks are due to G. Santini for his support of this work and the Region Picardie for their financial support.
PY - 2013/1
Y1 - 2013/1
N2 - The Suzuki-Miyaura coupling reaction is one of the most important synthetic catalytic reactions developed in the 20th century. However, the use of toxic organic solvents for this reaction still poses a scientific challenge and is an aspect of economical and ecological relevance. The use of water as a reaction medium overcomes this issue. In the present work, we described efficient Suzuki coupling reactions in water, without any phase transfer reagents and it is possible to couple challenging substrates like aryl chlorides. Notably, this protocol also works with ultra-low loading of catalyst with high turnover numbers. © 2012 Elsevier B.V.
AB - The Suzuki-Miyaura coupling reaction is one of the most important synthetic catalytic reactions developed in the 20th century. However, the use of toxic organic solvents for this reaction still poses a scientific challenge and is an aspect of economical and ecological relevance. The use of water as a reaction medium overcomes this issue. In the present work, we described efficient Suzuki coupling reactions in water, without any phase transfer reagents and it is possible to couple challenging substrates like aryl chlorides. Notably, this protocol also works with ultra-low loading of catalyst with high turnover numbers. © 2012 Elsevier B.V.
UR - http://hdl.handle.net/10754/562579
UR - https://linkinghub.elsevier.com/retrieve/pii/S0926860X12006394
UR - http://www.scopus.com/inward/record.url?scp=84872338399&partnerID=8YFLogxK
U2 - 10.1016/j.apcata.2012.09.046
DO - 10.1016/j.apcata.2012.09.046
M3 - Article
SN - 0926-860X
VL - 450
SP - 13
EP - 18
JO - Applied Catalysis A: General
JF - Applied Catalysis A: General
ER -