PARP1 Parylation Promotes Silent Locus Transmission in the Nucleolus: The Suspicion Confirmed

Maxim Isabelle, Imed Eddine Gallouzi, Guy G. Poirier

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Parylation modulates various processes, including transcription. In this issue of Molecular Cell, Guetg et al. (2012) show that, in the nucleolus, PARP1-mediated parylation of TIP5 promotes the silencing of rDNA chromatin during replication, uncovering the mechanism by which PARP1 ensures that silent rDNA regions are properly inherited. © 2012 Elsevier Inc..
Original languageEnglish (US)
Pages (from-to)706-707
Number of pages2
JournalMolecular Cell
Volume45
Issue number6
DOIs
StatePublished - Mar 30 2012
Externally publishedYes

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology

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