Pediatric 25-hydroxyvitamin D concentrationsin neurofibromatosis type 1

David A. Stevenson, David H. Viskochil, John C. Carey, Xiaoming Sheng, Mary Murray, Laurie Moyer-Mileur, Judd Shelton, William L. Roberts, Ashley M. Bunker, Heather Hanson, Stephanie Bauer, Jacques L.D. Astous

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

Objective: Low 25-hydroxyvitamin D (25OHD) concentrations have been associated with tumors and osteopenia or fractures in adults with neurofibromatosis type 1 (NF1). We report 25OHD concentrations in 109 children with NF1 and 218 controls matched for age, sex, geographic location, and time of year. Methods: Children with NF1 were recruited (n=109; 2-17 years), and clinical data and dual-energy X-ray absorptiometry measurements were obtained. 25OHD concentrations were measured in subjects and controls. Results: More NF1 individuals (50%) were in the 25OHD insufficient or deficient range (
Original languageEnglish (US)
Pages (from-to)169-174
Number of pages6
JournalJournal of Pediatric Endocrinology and Metabolism
Volume24
Issue number3-4
DOIs
StatePublished - Apr 1 2011
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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