Performance characteristics of the IMMULITE 2000 erythropoietin assay

William E. Owen; William L. Roberts

doi:10.1016/j.cccn.2003.11.005

Performance characteristics of the IMMULITE 2000 erythropoietin assay

William E. Owen, William L. Roberts

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

Background: Erythropoietin (EPO) is a glycoprotein hormone produced by specialized cells in the kidney that acts as the primary regulator of erythropoiesis. Serum EPO measurements are useful for diagnostic evaluations of anemia and polycythemia. Methods: The IMMULITE 2000 is an automated random access immunoassay analyzer for the central laboratory. The limit of detection (LOD), linearity, imprecision, comparison to another commercially available assay, and reference interval of a new EPO assay for this analyzer were assessed. Results: The LOD was 0.2 U/l. The assay was linear within an allowable systematic error of 10% over the range tested (2-178 U/l). The total imprecision of the new assay was

Original language	English (US)
Pages (from-to)	213-217
Number of pages	5
Journal	Clinica Chimica Acta
Volume	340
Issue number	1-2
DOIs	https://doi.org/10.1016/j.cccn.2003.11.005
State	Published - Jan 1 2004
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Clinical Biochemistry
Biochemistry, medical

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10.1016/j.cccn.2003.11.005

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abstract = "Background: Erythropoietin (EPO) is a glycoprotein hormone produced by specialized cells in the kidney that acts as the primary regulator of erythropoiesis. Serum EPO measurements are useful for diagnostic evaluations of anemia and polycythemia. Methods: The IMMULITE 2000 is an automated random access immunoassay analyzer for the central laboratory. The limit of detection (LOD), linearity, imprecision, comparison to another commercially available assay, and reference interval of a new EPO assay for this analyzer were assessed. Results: The LOD was 0.2 U/l. The assay was linear within an allowable systematic error of 10% over the range tested (2-178 U/l). The total imprecision of the new assay was",

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Performance characteristics of the IMMULITE 2000 erythropoietin assay

Abstract

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