TY - JOUR
T1 - Perspectives on the evolutionary origin of tetrapod limbs
AU - Capdevila, Javier
AU - Belmonte, Juan Carlos Izpisüa
PY - 2000/12/15
Y1 - 2000/12/15
N2 - The study of the origin and evolution of the tetrapod limb has benefited enormously from the confluence of molecular and paleontological data. In the last two decades, our knowledge of the basic molecular mechanisms that control limb development has grown exponentially, and developmental biologists now have the possibility of combining molecular data with many available descriptions of the fossil record of vertebrate fins and limbs. This synthesis of developmental and evolutionary biology has the potential to unveil the sequence of molecular changes that culminated in the adoption of the basic tetrapod limb plan. J. Exp. Zool. (Mol. Dev. Evol.) 288:287-303, 2000. (C) 2000 Wiley-Liss, Inc.
AB - The study of the origin and evolution of the tetrapod limb has benefited enormously from the confluence of molecular and paleontological data. In the last two decades, our knowledge of the basic molecular mechanisms that control limb development has grown exponentially, and developmental biologists now have the possibility of combining molecular data with many available descriptions of the fossil record of vertebrate fins and limbs. This synthesis of developmental and evolutionary biology has the potential to unveil the sequence of molecular changes that culminated in the adoption of the basic tetrapod limb plan. J. Exp. Zool. (Mol. Dev. Evol.) 288:287-303, 2000. (C) 2000 Wiley-Liss, Inc.
UR - http://www.scopus.com/inward/record.url?scp=0034672335&partnerID=8YFLogxK
U2 - 10.1002/1097-010X(20001215)288:4<287::AID-JEZ2>3.0.CO;2-5
DO - 10.1002/1097-010X(20001215)288:4<287::AID-JEZ2>3.0.CO;2-5
M3 - Review article
C2 - 11144278
AN - SCOPUS:0034672335
SN - 0022-104X
VL - 288
SP - 287
EP - 303
JO - Journal of Experimental Zoology
JF - Journal of Experimental Zoology
IS - 4
ER -