TY - JOUR
T1 - Phosphorylation-dependent regulation of plant chromatin and chromatin-associated proteins
AU - Bigeard, Jean
AU - Rayapuram, Naganand
AU - Pflieger, Delphine
AU - Hirt, Heribert
N1 - KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: This work was supported by the Agence Nationale de la Recherche (ANR-2010-JCJC-1608 to D. P.) and the Laboratory of Excellence Saclay Plant Sciences. We apologize for not citing many other published reports because of space limitations.
PY - 2014/7/10
Y1 - 2014/7/10
N2 - In eukaryotes, most of the DNA is located in the nucleus where it is organized with histone proteins in a higher order structure as chromatin. Chromatin and chromatin-associated proteins contribute to DNA-related processes such as replication and transcription as well as epigenetic regulation. Protein functions are often regulated by PTMs among which phosphorylation is one of the most abundant PTM. Phosphorylation of proteins affects important properties, such as enzyme activity, protein stability, or subcellular localization. We here describe the main specificities of protein phosphorylation in plants and review the current knowledge on phosphorylation-dependent regulation of plant chromatin and chromatin-associated proteins. We also outline some future challenges to further elucidate protein phosphorylation and chromatin regulation.
AB - In eukaryotes, most of the DNA is located in the nucleus where it is organized with histone proteins in a higher order structure as chromatin. Chromatin and chromatin-associated proteins contribute to DNA-related processes such as replication and transcription as well as epigenetic regulation. Protein functions are often regulated by PTMs among which phosphorylation is one of the most abundant PTM. Phosphorylation of proteins affects important properties, such as enzyme activity, protein stability, or subcellular localization. We here describe the main specificities of protein phosphorylation in plants and review the current knowledge on phosphorylation-dependent regulation of plant chromatin and chromatin-associated proteins. We also outline some future challenges to further elucidate protein phosphorylation and chromatin regulation.
UR - http://hdl.handle.net/10754/566147
UR - http://doi.wiley.com/10.1002/pmic.201400073
UR - http://www.scopus.com/inward/record.url?scp=84908056424&partnerID=8YFLogxK
U2 - 10.1002/pmic.201400073
DO - 10.1002/pmic.201400073
M3 - Article
SN - 1615-9853
VL - 14
SP - 2127
EP - 2140
JO - PROTEOMICS
JF - PROTEOMICS
IS - 19
ER -