Abstract
A visible light photoredox-catalyzed aldehyde olefin cyclization is reported. The method represents a formal hydroacylation of alkenes and alkynes and provides chromanol derivatives in good yields. The protocol takes advantage of the double role played by trialkylamines (NR3) which act as (i) electron donors for reducing the catalyst and (ii) proton donors to activate the substrate via a proton-coupled electron transfer. © 2016 American Chemical Society.
Original language | English (US) |
---|---|
Pages (from-to) | 6959-6964 |
Number of pages | 6 |
Journal | The Journal of Organic Chemistry |
Volume | 81 |
Issue number | 16 |
DOIs | |
State | Published - Jul 21 2016 |