Poly-ethers from Winogradskyella poriferorum: Antifouling potential, time-course study of production and natural abundance

Swagatika Dash; Yasuyuki Nogata; Xiaojian Zhou; Yifan Zhang; Ying Xü; Xian Rong Guo; Xixiang Zhang; Pei-Yuan Qian

doi:10.1016/j.biortech.2011.05.034

Poly-ethers from Winogradskyella poriferorum: Antifouling potential, time-course study of production and natural abundance

Swagatika Dash, Yasuyuki Nogata, Xiaojian Zhou, Yifan Zhang, Ying Xü, Xian Rong Guo, Xixiang Zhang, Pei-Yuan Qian

Research output: Contribution to journal › Article › peer-review

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Abstract

A sponge-associated bacterium, Winogradskyella poriferorum strain UST030701-295T was cultured up to 100l for extraction of antifouling bioactive compounds. Five poly-ethers were isolated and partially characterized based on nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS); two of them showed inhibitory effects on biofilm formation of marine bacteria and larval settlement of macro-foulers but did not produce any adverse effects on the phenotypes of zebra fish embryos at a concentration of 5μgml -1. The effect of culture duration on the production of the poly-ethers and the bioactivity of the relevant extracts was monitored over a period of 12days. The total crude poly-ether production increased from day 2 to day 5 and the highest bioactivity was observed on day 3. The poly-ethers were found to be localized in the cellular fraction of the extracts, implying their natural occurrence. The potent bioactivity of these poly-ethers together with their high natural abundance in bacteria makes them promising candidates as ingredients in antifouling applications. © 2011 Elsevier Ltd.

Original language	English (US)
Pages (from-to)	7532-7537
Number of pages	6
Journal	Bioresource Technology
Volume	102
Issue number	16
DOIs	https://doi.org/10.1016/j.biortech.2011.05.034
State	Published - Aug 2011

ASJC Scopus subject areas

Bioengineering
Environmental Engineering
Waste Management and Disposal

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10.1016/j.biortech.2011.05.034

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title = "Poly-ethers from Winogradskyella poriferorum: Antifouling potential, time-course study of production and natural abundance",

abstract = "A sponge-associated bacterium, Winogradskyella poriferorum strain UST030701-295T was cultured up to 100l for extraction of antifouling bioactive compounds. Five poly-ethers were isolated and partially characterized based on nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS); two of them showed inhibitory effects on biofilm formation of marine bacteria and larval settlement of macro-foulers but did not produce any adverse effects on the phenotypes of zebra fish embryos at a concentration of 5μgml -1. The effect of culture duration on the production of the poly-ethers and the bioactivity of the relevant extracts was monitored over a period of 12days. The total crude poly-ether production increased from day 2 to day 5 and the highest bioactivity was observed on day 3. The poly-ethers were found to be localized in the cellular fraction of the extracts, implying their natural occurrence. The potent bioactivity of these poly-ethers together with their high natural abundance in bacteria makes them promising candidates as ingredients in antifouling applications. {\textcopyright} 2011 Elsevier Ltd.",

author = "Swagatika Dash and Yasuyuki Nogata and Xiaojian Zhou and Yifan Zhang and Ying X{\"u} and Guo, {Xian Rong} and Xixiang Zhang and Pei-Yuan Qian",

note = "KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: The authors thank Dr. Shawn Arellano and Ms. Cherry Kwan for proof reading and providing their valuable comments during the manuscript preparation. We also acknowledge Li Jie Sun (HKUST) and Yu Liang Yang (SIO, USA) for their technical assistance in NMR and MS data acquisition, Dr. Zilong Wen (HKUST) for providing the zebra fish embryo and Dr. Liu Xin for all the helpful discussions. This work was supported by the CAS/SAFEA International Partnership Program for Creative Research Teams KZCX2-YW-T001) and an award SA-C0040/UK-C0016 from the King Abdullah University of Science and Technology to Pei-Yuan Qian.",

year = "2011",

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AU - Dash, Swagatika

AU - Nogata, Yasuyuki

AU - Zhou, Xiaojian

AU - Zhang, Yifan

AU - Xü, Ying

AU - Guo, Xian Rong

AU - Zhang, Xixiang

AU - Qian, Pei-Yuan

N1 - KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: The authors thank Dr. Shawn Arellano and Ms. Cherry Kwan for proof reading and providing their valuable comments during the manuscript preparation. We also acknowledge Li Jie Sun (HKUST) and Yu Liang Yang (SIO, USA) for their technical assistance in NMR and MS data acquisition, Dr. Zilong Wen (HKUST) for providing the zebra fish embryo and Dr. Liu Xin for all the helpful discussions. This work was supported by the CAS/SAFEA International Partnership Program for Creative Research Teams KZCX2-YW-T001) and an award SA-C0040/UK-C0016 from the King Abdullah University of Science and Technology to Pei-Yuan Qian.

PY - 2011/8

Y1 - 2011/8

N2 - A sponge-associated bacterium, Winogradskyella poriferorum strain UST030701-295T was cultured up to 100l for extraction of antifouling bioactive compounds. Five poly-ethers were isolated and partially characterized based on nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS); two of them showed inhibitory effects on biofilm formation of marine bacteria and larval settlement of macro-foulers but did not produce any adverse effects on the phenotypes of zebra fish embryos at a concentration of 5μgml -1. The effect of culture duration on the production of the poly-ethers and the bioactivity of the relevant extracts was monitored over a period of 12days. The total crude poly-ether production increased from day 2 to day 5 and the highest bioactivity was observed on day 3. The poly-ethers were found to be localized in the cellular fraction of the extracts, implying their natural occurrence. The potent bioactivity of these poly-ethers together with their high natural abundance in bacteria makes them promising candidates as ingredients in antifouling applications. © 2011 Elsevier Ltd.

AB - A sponge-associated bacterium, Winogradskyella poriferorum strain UST030701-295T was cultured up to 100l for extraction of antifouling bioactive compounds. Five poly-ethers were isolated and partially characterized based on nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS); two of them showed inhibitory effects on biofilm formation of marine bacteria and larval settlement of macro-foulers but did not produce any adverse effects on the phenotypes of zebra fish embryos at a concentration of 5μgml -1. The effect of culture duration on the production of the poly-ethers and the bioactivity of the relevant extracts was monitored over a period of 12days. The total crude poly-ether production increased from day 2 to day 5 and the highest bioactivity was observed on day 3. The poly-ethers were found to be localized in the cellular fraction of the extracts, implying their natural occurrence. The potent bioactivity of these poly-ethers together with their high natural abundance in bacteria makes them promising candidates as ingredients in antifouling applications. © 2011 Elsevier Ltd.

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Poly-ethers from Winogradskyella poriferorum: Antifouling potential, time-course study of production and natural abundance

Abstract

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