Polyethylenimine-grafted multiwalled carbon nanotubes for secure noncovalent immobilization and efficient delivery of DNA

Ye Liu; De Cheng Wu; Wei De Zhang; Xuan Jiang; Chao Bin He; Tai Shung Chung; Suat Hong Goh; Kam W. Leong

doi:10.1002/anie.200500042

Polyethylenimine-grafted multiwalled carbon nanotubes for secure noncovalent immobilization and efficient delivery of DNA

Ye Liu^*, De Cheng Wu, Wei De Zhang, Xuan Jiang, Chao Bin He, Tai Shung Chung, Suat Hong Goh, Kam W. Leong

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

356 Scopus citations

Abstract

(Figure Presented) DNA hits the wall: DNA is immobilized securely onto the surface of multiwalled carbon nanotubes through electrostatic interactions with grafted polyethylenimine (PEI; see picture). The polyethylenimine-graft multiwalled carbon nanotubes carrying DNA show transfection efficiency for DNA delivery similar to or even several times higher than PEI.

Original language	English (US)
Pages (from-to)	4782-4785
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	44
Issue number	30
DOIs	https://doi.org/10.1002/anie.200500042
State	Published - Jul 25 2005
Externally published	Yes

Keywords

Amines
Carbon nanotubes
DNA
Gene technology
Polymerization

ASJC Scopus subject areas

General Chemistry
Catalysis

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10.1002/anie.200500042

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abstract = "(Figure Presented) DNA hits the wall: DNA is immobilized securely onto the surface of multiwalled carbon nanotubes through electrostatic interactions with grafted polyethylenimine (PEI; see picture). The polyethylenimine-graft multiwalled carbon nanotubes carrying DNA show transfection efficiency for DNA delivery similar to or even several times higher than PEI.",

keywords = "Amines, Carbon nanotubes, DNA, Gene technology, Polymerization",

author = "Ye Liu and Wu, {De Cheng} and Zhang, {Wei De} and Xuan Jiang and He, {Chao Bin} and Chung, {Tai Shung} and Goh, {Suat Hong} and Leong, {Kam W.}",

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AU - Liu, Ye

AU - Wu, De Cheng

AU - Zhang, Wei De

AU - Jiang, Xuan

AU - He, Chao Bin

AU - Chung, Tai Shung

AU - Goh, Suat Hong

AU - Leong, Kam W.

PY - 2005/7/25

Y1 - 2005/7/25

N2 - (Figure Presented) DNA hits the wall: DNA is immobilized securely onto the surface of multiwalled carbon nanotubes through electrostatic interactions with grafted polyethylenimine (PEI; see picture). The polyethylenimine-graft multiwalled carbon nanotubes carrying DNA show transfection efficiency for DNA delivery similar to or even several times higher than PEI.

AB - (Figure Presented) DNA hits the wall: DNA is immobilized securely onto the surface of multiwalled carbon nanotubes through electrostatic interactions with grafted polyethylenimine (PEI; see picture). The polyethylenimine-graft multiwalled carbon nanotubes carrying DNA show transfection efficiency for DNA delivery similar to or even several times higher than PEI.

KW - Amines

KW - Carbon nanotubes

KW - DNA

KW - Gene technology

KW - Polymerization

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Polyethylenimine-grafted multiwalled carbon nanotubes for secure noncovalent immobilization and efficient delivery of DNA

Abstract

Keywords

ASJC Scopus subject areas

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