TY - JOUR
T1 - Preparation of a Highly Conductive Seed Layer for Calcium Sensor Fabrication with Enhanced Sensing Performance
AU - Ahmad, Rafiq
AU - Tripathy, Nirmalya
AU - Ahn, Min-Sang
AU - Yoo, Jin-Young
AU - Hahn, Yoon-Bong
N1 - KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: This work was supported by the National Leading Research Laboratory program through the National Research Foundation (NRF) (NRF-2016R1A2B2016665) of Korea funded by the Ministry of Science, ICT & Future Planning. Authors also thank KBSI, Jeonju branch for SEM analysis and Mr. Jong-Gyun Kang, Center for University Research Facility (CURF) for taking good quality TEM images.
PY - 2018/3/16
Y1 - 2018/3/16
N2 - The seed layer plays a crucial role in achieving high electrical conductivity and ensuring higher performance of devices. In this study, we report fabrication of a solution-gated field-effect transistor (FET) sensor based on zinc oxide nanorods (ZnO NRs) modified iron oxide nanoparticles (α-FeO NPs) grown on a highly conductive sandwich-like seed layer (ZnO seed layer/Ag nanowires/ZnO seed layer). The sandwich-like seed layer and ZnO NRs modification with α-FeO NPs provide excellent conductivity and prevent possible ZnO NRs surface damage from low pH enzyme immobilization, respectively. The highly conductive solution-gated FET sensor employed the calmodulin (CaM) immobilization on the surface of α-FeO-ZnO NRs for selective detection of calcium ions (Ca). The solution-gated FET sensor exhibited a substantial change in conductance upon introduction of different concentrations of Ca and showed high sensitivity (416.8 μA cm mM) and wide linear range (0.01-3.0 mM). In addition, the total Ca concentration in water and serum samples was also measured. Compared to the analytically obtained data, our sensor was found to measure Ca in the water and serum samples accurately, suggesting a potential alternative for Ca determination in water and serum samples, specifically used for drinking/irrigation and clinical analysis.
AB - The seed layer plays a crucial role in achieving high electrical conductivity and ensuring higher performance of devices. In this study, we report fabrication of a solution-gated field-effect transistor (FET) sensor based on zinc oxide nanorods (ZnO NRs) modified iron oxide nanoparticles (α-FeO NPs) grown on a highly conductive sandwich-like seed layer (ZnO seed layer/Ag nanowires/ZnO seed layer). The sandwich-like seed layer and ZnO NRs modification with α-FeO NPs provide excellent conductivity and prevent possible ZnO NRs surface damage from low pH enzyme immobilization, respectively. The highly conductive solution-gated FET sensor employed the calmodulin (CaM) immobilization on the surface of α-FeO-ZnO NRs for selective detection of calcium ions (Ca). The solution-gated FET sensor exhibited a substantial change in conductance upon introduction of different concentrations of Ca and showed high sensitivity (416.8 μA cm mM) and wide linear range (0.01-3.0 mM). In addition, the total Ca concentration in water and serum samples was also measured. Compared to the analytically obtained data, our sensor was found to measure Ca in the water and serum samples accurately, suggesting a potential alternative for Ca determination in water and serum samples, specifically used for drinking/irrigation and clinical analysis.
UR - http://hdl.handle.net/10754/627755
UR - https://pubs.acs.org/doi/10.1021/acssensors.7b00900
UR - http://www.scopus.com/inward/record.url?scp=85045945851&partnerID=8YFLogxK
U2 - 10.1021/acssensors.7b00900
DO - 10.1021/acssensors.7b00900
M3 - Article
SN - 2379-3694
VL - 3
SP - 772
EP - 778
JO - ACS Sensors
JF - ACS Sensors
IS - 4
ER -