TY - JOUR
T1 - Prevalence of Helicobacter pylori DNA in recurrent aphthous ulcerations in mucosa-associated lymphoid tissues of the pharynx
AU - Elsheikh, Mohamed Nasser
AU - Mahfouz, Magdy El Sayed
N1 - Generated from Scopus record by KAUST IRTS on 2023-09-25
PY - 2005/9/1
Y1 - 2005/9/1
N2 - Objective: To determine the presence of Helicobacter pylori and, if detected, its potential prevalence in causing recurrent aphthous ulcers confined to mucosa-associated lymphoid tissues of the pharynx. Design: Prospective, controlled clinical trial. Setting: Otolaryngology Department of Tanta University Hospitals, Tanta, Egypt. Patients: A total of 146 patients with recurrent multiple aphthous ulcers of the oral cavity and pharynx and 20 normal control subjects. Interventions: Patients were assigned to group 1 (n=58), in which the ulcers were strictly limited to the lymphoid tissues, or group 2 (n=88), in which the ulcers were randomly distributed in the oral cavity and pharynx. Helicobacter pylori DNA was extracted from 3-mm-diameter tissue samples, and polymerase chain reaction amplifications were performed for the 16S ribosomal RNA gene. Main Outcome Measure: Positivity for H pylori. Results: In group 1, 39 patients (67%) were positive for H pylori DNA, while in group 2, 9 patients (10%) were positive (X2 test, P
AB - Objective: To determine the presence of Helicobacter pylori and, if detected, its potential prevalence in causing recurrent aphthous ulcers confined to mucosa-associated lymphoid tissues of the pharynx. Design: Prospective, controlled clinical trial. Setting: Otolaryngology Department of Tanta University Hospitals, Tanta, Egypt. Patients: A total of 146 patients with recurrent multiple aphthous ulcers of the oral cavity and pharynx and 20 normal control subjects. Interventions: Patients were assigned to group 1 (n=58), in which the ulcers were strictly limited to the lymphoid tissues, or group 2 (n=88), in which the ulcers were randomly distributed in the oral cavity and pharynx. Helicobacter pylori DNA was extracted from 3-mm-diameter tissue samples, and polymerase chain reaction amplifications were performed for the 16S ribosomal RNA gene. Main Outcome Measure: Positivity for H pylori. Results: In group 1, 39 patients (67%) were positive for H pylori DNA, while in group 2, 9 patients (10%) were positive (X2 test, P
UR - http://archotol.jamanetwork.com/article.aspx?doi=10.1001/archotol.131.9.804
UR - http://www.scopus.com/inward/record.url?scp=25444488504&partnerID=8YFLogxK
U2 - 10.1001/archotol.131.9.804
DO - 10.1001/archotol.131.9.804
M3 - Article
SN - 0886-4470
VL - 131
SP - 804
EP - 808
JO - Archives of Otolaryngology - Head and Neck Surgery
JF - Archives of Otolaryngology - Head and Neck Surgery
IS - 9
ER -