R we there yet? Advances in cloning resistance genes for engineering immunity in crop plants

Renjie Chen, Karthick Gajendiran, Brande B.H. Wulff*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations

Abstract

Over the past three decades, significant progress has been made in the field of resistance (R) gene cloning. Advances in recombinant DNA technology, genome sequencing, bioinformatics, plant transformation and plant husbandry have facilitated the transition from cloning R genes in model species to crop plants and their wild relatives. To date, researchers have isolated more than 450 R genes that play important roles in plant immunity. The molecular and biochemical mechanisms by which intracellular immune receptors are activated and initiate defense responses are now well understood. These advances present exciting opportunities for engineering disease-resistant crop plants that are protected by genetics rather than pesticides.

Original languageEnglish (US)
Article number102489
JournalCurrent Opinion in Plant Biology
Volume77
DOIs
StatePublished - Feb 2024

ASJC Scopus subject areas

  • Plant Science

Fingerprint

Dive into the research topics of 'R we there yet? Advances in cloning resistance genes for engineering immunity in crop plants'. Together they form a unique fingerprint.

Cite this