Raman spectroscopy for detection of stretched DNAs on superhydrophobic surfaces

Monica Marini; Gobind Das; Rosanna La Rocca; Francesco T. Gentile; Tania Limongi; Stefania Santoriello; Alice Scarpellini; Enzo M. Di Fabrizio

doi:10.1016/j.mee.2014.04.008

Raman spectroscopy for detection of stretched DNAs on superhydrophobic surfaces

Monica Marini, Gobind Das, Rosanna La Rocca, Francesco T. Gentile, Tania Limongi, Stefania Santoriello, Alice Scarpellini, Enzo M. Di Fabrizio

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

A novel approach for the study of low concentrated DNAs (60 pM) using microRaman spectroscopy is reported. A superhydrophobic substrate with array of microPillars is fabricated over which the sample was drop casted. The substrate concentrates the molecules in a very small area with higher molecular density, enabling to carry out the microRaman measurements. Two different DNAs (single strand and double strand) were used to investigate through Raman technique. A spectral Raman difference was found to distinguish the ssDNA and dsDNAs. The approach can be of interest for a wide variety of applications ranging from biological materials interactions characterization to the biomedical field. © 2014 Elsevier B.V. All rights reserved.

Original language	English (US)
Pages (from-to)	151-154
Number of pages	4
Journal	Microelectronic Engineering
Volume	119
DOIs	https://doi.org/10.1016/j.mee.2014.04.008
State	Published - May 2014

ASJC Scopus subject areas

Surfaces, Coatings and Films
Atomic and Molecular Physics, and Optics
Electronic, Optical and Magnetic Materials
Electrical and Electronic Engineering
Condensed Matter Physics

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10.1016/j.mee.2014.04.008

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title = "Raman spectroscopy for detection of stretched DNAs on superhydrophobic surfaces",

abstract = "A novel approach for the study of low concentrated DNAs (60 pM) using microRaman spectroscopy is reported. A superhydrophobic substrate with array of microPillars is fabricated over which the sample was drop casted. The substrate concentrates the molecules in a very small area with higher molecular density, enabling to carry out the microRaman measurements. Two different DNAs (single strand and double strand) were used to investigate through Raman technique. A spectral Raman difference was found to distinguish the ssDNA and dsDNAs. The approach can be of interest for a wide variety of applications ranging from biological materials interactions characterization to the biomedical field. {\textcopyright} 2014 Elsevier B.V. All rights reserved.",

author = "Monica Marini and Gobind Das and {La Rocca}, Rosanna and Gentile, {Francesco T.} and Tania Limongi and Stefania Santoriello and Alice Scarpellini and {Di Fabrizio}, {Enzo M.}",

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T1 - Raman spectroscopy for detection of stretched DNAs on superhydrophobic surfaces

AU - Marini, Monica

AU - Das, Gobind

AU - La Rocca, Rosanna

AU - Gentile, Francesco T.

AU - Limongi, Tania

AU - Santoriello, Stefania

AU - Scarpellini, Alice

AU - Di Fabrizio, Enzo M.

N1 - KAUST Repository Item: Exported on 2020-10-01

PY - 2014/5

Y1 - 2014/5

N2 - A novel approach for the study of low concentrated DNAs (60 pM) using microRaman spectroscopy is reported. A superhydrophobic substrate with array of microPillars is fabricated over which the sample was drop casted. The substrate concentrates the molecules in a very small area with higher molecular density, enabling to carry out the microRaman measurements. Two different DNAs (single strand and double strand) were used to investigate through Raman technique. A spectral Raman difference was found to distinguish the ssDNA and dsDNAs. The approach can be of interest for a wide variety of applications ranging from biological materials interactions characterization to the biomedical field. © 2014 Elsevier B.V. All rights reserved.

AB - A novel approach for the study of low concentrated DNAs (60 pM) using microRaman spectroscopy is reported. A superhydrophobic substrate with array of microPillars is fabricated over which the sample was drop casted. The substrate concentrates the molecules in a very small area with higher molecular density, enabling to carry out the microRaman measurements. Two different DNAs (single strand and double strand) were used to investigate through Raman technique. A spectral Raman difference was found to distinguish the ssDNA and dsDNAs. The approach can be of interest for a wide variety of applications ranging from biological materials interactions characterization to the biomedical field. © 2014 Elsevier B.V. All rights reserved.

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VL - 119

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JO - Microelectronic Engineering

JF - Microelectronic Engineering

ER -

Raman spectroscopy for detection of stretched DNAs on superhydrophobic surfaces

Abstract

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